Brain-on-Chip (BoC) biotechnology is emerging as a promising tool for biomedical and
pharmaceutical research applied to the neurosciences. At the convergence between lab-on …

Chronic imaging of neuronal networks in vitro has provided fundamental insights into
mechanisms underlying neuronal function. Current labeling and optical imaging methods …

The electrophysiological technology having a high spatiotemporal resolution at the single‐
cell level and noninvasive measurements of large areas provide insights on underlying …

Electrophysiological research on neural networks and their activity focuses on the recording
and analysis of large data sets that include information of thousands of neurons. CMOS …

Axons convey information in neuronal circuits via reliable conduction of action potentials
(APs) from the axon initial segment (AIS) to the presynaptic terminals. Recent experimental …

The tri-synaptic pathway in the mammalian hippocampus enables cognitive learning and
memory. Despite decades of reports on anatomy and physiology, the functional architecture …

This article presents a fully integrated multi-modal CMOS cellular sensor/stimulator array
chip with 21 952 pixels and 1568-pixel concurrent readouts, while each array pixel can be …

Objective: Neurons communicate with each other by sending action potentials (APs) through
their axons. The velocity of axonal signal propagation describes how fast electrical APs can …

High-density microelectrode arrays (HD-MEAs) are increasingly being used for the
observation and manipulation of neurons and networks in vitro. Large-scale electrode arrays …

This paper presents a 1024-channel neural read-out integrated circuit (ROIC) for solution-
gated GFET sensing probes in massive ECoG brain map**. The proposed time-domain …