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Gold complexes in anticancer therapy: from new design principles to particle‐based delivery systems
The discovery of the medicinal properties of gold complexes has fuelled the design and
synthesis of new anticancer metallodrugs, which have received special attention due to their …
synthesis of new anticancer metallodrugs, which have received special attention due to their …
Recent development of gold (I) and gold (III) complexes as therapeutic agents for cancer diseases
Y Lu, X Ma, X Chang, Z Liang, L Lv, M Shan… - Chemical Society …, 2022 - pubs.rsc.org
Metal complexes have demonstrated significant antitumor activities and platinum complexes
are well established in the clinical application of cancer chemotherapy. However, the …
are well established in the clinical application of cancer chemotherapy. However, the …
Riding the metal wave: A review of the latest developments in metal-based anticancer agents
Metal-based complexes have demonstrated significant anticancer effects and have emerged
as candidates with great potential for cancer therapy. These agents are effective in a variety …
as candidates with great potential for cancer therapy. These agents are effective in a variety …
Recent advances in gold–NHC complexes with biological properties
This tutorial review covers the recent advances made in the study of gold complexes
containing N-heterocyclic carbene ligands with biological properties. The great stability …
containing N-heterocyclic carbene ligands with biological properties. The great stability …
Preparation and Post-Assembly Modification of Metallosupramolecular Assemblies from Poly(N-Heterocyclic Carbene) Ligands
MM Gan, JQ Liu, L Zhang, YY Wang, FE Hahn… - Chemical …, 2018 - ACS Publications
Although the coordination chemistry of N-heterocyclic carbenes (NHCs) with transition
metals has been explored for half a century, only in the past ten years has the chemistry of …
metals has been explored for half a century, only in the past ten years has the chemistry of …
Metal complex interactions with DNA
Increasing numbers of DNA structures are being revealed using biophysical, spectroscopic
and genomic methods. The diversity of transition metal complexes is also growing, as the …
and genomic methods. The diversity of transition metal complexes is also growing, as the …
Organometallic anticancer compounds
The quest for alternative drugs to the well-known cisplatin and its derivatives, which are still
used in more than 50% of the treatment regimes for patients suffering from cancer, is highly …
used in more than 50% of the treatment regimes for patients suffering from cancer, is highly …
Metal N-heterocyclic carbene complexes as potential antitumor metallodrugs
W Liu, R Gust - Chemical Society Reviews, 2013 - pubs.rsc.org
The discovery of cisplatin's antitumor activity in 1969 prompted the search for novel metal-
containing complexes as potential anticancer drugs. Among these novel complexes, metal N …
containing complexes as potential anticancer drugs. Among these novel complexes, metal N …
N-Heterocyclic carbene metal complexes in medicinal chemistry
L Oehninger, R Rubbiani, I Ott - Dalton Transactions, 2013 - pubs.rsc.org
Metal complexes with N-heterocyclic carbene (NHC) ligands are widely used in chemistry
due to their catalytic properties and applied for olefin metathesis among other reactions. The …
due to their catalytic properties and applied for olefin metathesis among other reactions. The …
A promising future of metal‐N‐heterocyclic carbene complexes in medicinal chemistry: The emerging bioorganometallic antitumor agents
Q Zhao, B Han, C Peng, N Zhang… - Medicinal Research …, 2024 - Wiley Online Library
Metal complexes based on N‐heterocyclic carbene (NHC) ligands have emerged as
promising broad‐spectrum antitumor agents in bioorganometallic medicinal chemistry. In …
promising broad‐spectrum antitumor agents in bioorganometallic medicinal chemistry. In …