The implementation of TNFRSF co-stimulatory domains in CAR-T cells for optimal functional activity
Simple Summary Members of the Tumor Necrosis Factor Receptor Superfamily (TNFRSF)
provide crucial co-stimulatory signals to many if not all immune effector cells. With distinct …
provide crucial co-stimulatory signals to many if not all immune effector cells. With distinct …
Modular pooled discovery of synthetic knockin sequences to program durable cell therapies
Chronic stimulation can cause T cell dysfunction and limit the efficacy of cellular
immunotherapies. Improved methods are required to compare large numbers of synthetic …
immunotherapies. Improved methods are required to compare large numbers of synthetic …
Novel T cell biomarkers and the development of immunotherapeutic anti-tumor strategies
M Vlaming - 2023 - research.rug.nl
The past decade has seen a rapid progress in identifying the complex tumor-immune
interactions that occur in the tumor micro-environment (TME), on the basis of which …
interactions that occur in the tumor micro-environment (TME), on the basis of which …