Caveolin-1 in oncogenic transformation, cancer, and metastasis
Caveolae are 50-to 100-nm omega-shaped invaginations of the plasma membrane that
function as regulators of signal transduction. Caveolins are a class of oligomeric structural …
function as regulators of signal transduction. Caveolins are a class of oligomeric structural …
Warburg Meets Autophagy: Cancer-Associated Fibroblasts Accelerate Tumor Growth and Metastasis via Oxidative Stress, Mitophagy, and Aerobic Glycolysis
S Pavlides, I Vera, R Gandara, S Sneddon… - Antioxidants & redox …, 2012 - liebertpub.com
Significance: Here, we review certain recent advances in oxidative stress and tumor
metabolism, which are related to understanding the contributions of the microenvironment in …
metabolism, which are related to understanding the contributions of the microenvironment in …
Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms
F Sotgia, UE Martinez-Outschoorn… - Annual Review of …, 2012 - annualreviews.org
Caveolins are a family of membrane-bound scaffolding proteins that compartmentalize and
negatively regulate signal transduction. Recent studies have implicated a loss of caveolin-1 …
negatively regulate signal transduction. Recent studies have implicated a loss of caveolin-1 …
Caveolae-mediated endocytosis is critical for albumin cellular uptake and response to albumin-bound chemotherapy
Nab-paclitaxel, a nanoparticle conjugate of paclitaxel to human albumin, exhibits efficacy in
pancreatic cancer, non–small cell lung cancer and breast cancer. However, there is a lack of …
pancreatic cancer, non–small cell lung cancer and breast cancer. However, there is a lack of …
Caveolin-1 in tumor progression: the good, the bad and the ugly
Abstract Caveolin-1 (Cav1) is a multifunctional scaffolding protein with multiple binding
partners that is associated with cell surface caveolae and the regulation of lipid raft domains …
partners that is associated with cell surface caveolae and the regulation of lipid raft domains …
Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix
We have previously characterized human smooth muscle myosin light chain (MLC)-2
isoform by complementary DNA cloning and have shown that this isoform is expressed in a …
isoform by complementary DNA cloning and have shown that this isoform is expressed in a …
Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1
S Luanpitpong, SJ Talbott, Y Rojanasakul… - Journal of Biological …, 2010 - ASBMB
The acquired capability of tumor cells to migrate and invade neighboring tissues is
associated with high metastatic potential and advanced stage of cancers. Recently …
associated with high metastatic potential and advanced stage of cancers. Recently …
Caveolin‐1, cancer and therapy resistance
J Ketteler, D Klein - International journal of cancer, 2018 - Wiley Online Library
Resistance of solid tumors to chemo‐and radiotherapy remains a major obstacle in anti‐
cancer treatment. Herein, the membrane protein caveolin‐1 (CAV1) came into focus as it is …
cancer treatment. Herein, the membrane protein caveolin‐1 (CAV1) came into focus as it is …
Stromal cell expression of caveolin-1 predicts outcome in breast cancer
Caveolin-1 has been linked to tumor progression and clinical outcome in breast cancer, but
a clear resolution of its role as a prognostic marker is lacking. We assessed caveolin-1 …
a clear resolution of its role as a prognostic marker is lacking. We assessed caveolin-1 …
Albumin nanoparticles surface decorated with a tumor-homing peptide help in selective killing of triple-negative breast cancer cells
In this article, we describe a method of delivery of doxorubicin using a novel tumor-homing
peptide-based albumin nanoparticle system to triple-negative breast cancer cells (TNBC) …
peptide-based albumin nanoparticle system to triple-negative breast cancer cells (TNBC) …