Coronary artery atherosclerosis is a local, multifactorial, complex disease, and the leading
cause of death in the US. Complex interactions between biochemical transport and …

Extracellular ATP has been proposed to act as a danger signal to alert the immune system of
cell damage. Release of high local concentrations of ATP activates the nucleotide receptor …

Background In vivo studies have demonstrated that reasonable exercise training can
improve endothelial function. To confirm the key role of wall shear stress induced by …

To reproduce hemodynamic stress microenvironments of endothelial cells in vitro is of vital
significance, by which one could exploit the quantitative impact of hemodynamic stresses on …

The mechanically induced release of adenosine-5′-triphosphate (ATP) from osteoblastic
cells (MC3T3-E1) was measured in real time. A stretching device integrated into scanning …

Intracellular calcium dynamics plays an important role in the regulation of vascular
endothelial cellular functions. In order to probe the intracellular calcium dynamic response …

Generating precise in vivo arterial endothelial hemodynamic microenvironments using
microfluidics is essential for exploring endothelial mechanobiology. However, a …

The importance of the endothelium in the local regulation of blood flow is reflected by its
influence on vascular tone by means of vasodilatory responses to many physiological …

The calcium signaling plays a vital role in flow-dependent vascular endothelial cell (VEC)
physiology. Variations in fluid shear stress and ATP concentration in blood vessels can …

[Frontiers in Bioscience, Elite, 5, 130-140, January 1, 2013] 130 Hematopoietic modulators as
potential agents for the treatment Page 1 [Frontiers in Bioscience, Elite, 5, 130-140, January 1 …