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A research definition and framework for acute paediatric critical illness across resource-variable settings: a modified Delphi consensus
The true global burden of paediatric critical illness remains unknown. Studies on children
with life-threatening conditions are hindered by the absence of a common definition for …
with life-threatening conditions are hindered by the absence of a common definition for …
Contextual factors influencing bubble continuous positive airway pressure implementation for paediatric respiratory distress in low-income and middle-income …
Background Bubble continuous positive airway pressure (bCPAP) is a low-cost, non-
invasive respiratory support therapy for children with respiratory distress, but its …
invasive respiratory support therapy for children with respiratory distress, but its …
Association between age and mortality in pediatric and adult acute respiratory distress syndrome
Rationale: The epidemiology, management, and outcomes of acute respiratory distress
syndrome (ARDS) differ between children and adults, with lower mortality rates in children …
syndrome (ARDS) differ between children and adults, with lower mortality rates in children …
AARC Clinical practice guideline: patient-ventilator assessment
Given the important role of patient-ventilator assessments in ensuring the safety and efficacy
of mechanical ventilation, a team of respiratory therapists and a librarian used Grading of …
of mechanical ventilation, a team of respiratory therapists and a librarian used Grading of …
Building global collaborative research networks in paediatric critical care: A roadmap
Paediatric critical care units are designed for children at a vulnerable stage of development,
yet the evidence base for practice and policy in paediatric critical care remains scarce. In this …
yet the evidence base for practice and policy in paediatric critical care remains scarce. In this …
Critical illness-related corticosteroid insufficiency (CIRCI) in paediatric patients: a diagnostic and therapeutic challenge
Critical illness-related corticosteroid insufficiency or CIRCI is characterized by acute and life-
threatening disfunction of hypothalamic–pituitary–adrenal (HPA) axis observed among …
threatening disfunction of hypothalamic–pituitary–adrenal (HPA) axis observed among …
Assessing clinical improvement of infants hospitalized for respiratory syncytial virus-related critical illness
SB Leland, LD Zambrano, SJ Staffa… - The Journal of …, 2025 - academic.oup.com
Background Pediatric respiratory syncytial virus (RSV)-related acute lower respiratory tract
infection (LRTI) commonly requires hospitalization. The Clinical Progression Scale …
infection (LRTI) commonly requires hospitalization. The Clinical Progression Scale …
Implementation science research in pediatric critical care medicine
OBJECTIVES: Delay or failure to consistently adopt evidence-based or consensus-based
best practices into routine clinical care is common, including for patients in the PICU. PICU …
best practices into routine clinical care is common, including for patients in the PICU. PICU …
Endothelial glycocalyx degradation patterns in sepsis-associated pediatric acute respiratory distress syndrome: a single center retrospective observational study
Background Sepsis-associated destruction of the pulmonary microvascular endothelial
glycocalyx (EGCX) creates a vulnerable endothelial surface, contributing to the development …
glycocalyx (EGCX) creates a vulnerable endothelial surface, contributing to the development …
Acute respiratory distress syndrome: A review of ARDS across the life course
C Cave, D Samano, AM Sharma… - Journal of …, 2024 - journals.sagepub.com
Acute respiratory distress syndrome (ARDS) is a multifactorial, inflammatory lung disease
with significant morbidity and mortality that predominantly requires supportive care in its …
with significant morbidity and mortality that predominantly requires supportive care in its …