Metallothioneins (MTs) are small cysteine-rich proteins that play important roles in metal
homeostasis and protection against heavy metal toxicity, DNA damage, and oxidative stress …

MT1 has been demonstrated to be an essential stress protein in maintaining physiological
balance and regulating immune homeostasis. While the immunological involvement of MT1 …

Around 3000 proteins are thought to bind zinc in vivo, which corresponds to~ 10% of the
human proteome. Zinc plays a pivotal role as a structural, catalytic, and signaling component …

Free radicals are chemical particles containing one or more unpaired electrons, which may
be part of the molecule. They cause the molecule to become highly reactive. The free …

Zn2+ ions are essential in many physiological processes, including enzyme catalysis,
protein structural stabilization, and the regulation of many proteins. The affinities of proteins …

The biological effects of environmental metal contamination are important issues in an
industrialized, resource-dependent world. Different metals have different roles in biology …

Transition metals, such as iron, copper, and zinc, play a very important role in life as the
regulators of various physiochemical reactions in cells. Abnormal distribution and …

The human eye, the highly specialized organ of vision, is greatly influenced by oxidants of
endogenous and exogenous origin. Oxidative stress affects all structures of the human eye …

Numerous nutritional factors increase the risk of hepatocellular carcinoma (HCC)
development. The dysregulation of zinc, copper, and selenium homeostasis is associated …

Metallothioneins (MTs) are ubiquitous low molecular weight cysteine-rich proteins
characterized by high affinity for d10 electron configuration metals, including essential (Zn …