Effects of urban living environments on mental health in adults
J Xu, N Liu, E Polemiti, L Garcia-Mondragon, J Tang… - Nature medicine, 2023 - nature.com
Urban-living individuals are exposed to many environmental factors that may combine and
interact to influence mental health. While individual factors of an urban environment have …
interact to influence mental health. While individual factors of an urban environment have …
Biological factors underpinning suicidal behaviour: an update
Suicide, a global health burden, represents the 17th leading cause of death worldwide
(1.3%), but the 4th among young people aged between 15 and 29 years of age, according to …
(1.3%), but the 4th among young people aged between 15 and 29 years of age, according to …
[HTML][HTML] Luteolin and its antidepressant properties: From mechanism of action to potential therapeutic application
J Zhou, Z Wu, P Zhao - Journal of Pharmaceutical Analysis, 2024 - Elsevier
Luteolin is a natural flavonoid compound exists in various fruits and vegetables. Recent
studies have indicated that luteolin has variety pharmacological effects, including a wide …
studies have indicated that luteolin has variety pharmacological effects, including a wide …
Integrative analyses of scRNA-seq, bulk mRNA-seq, and DNA methylation profiling in depressed suicide brain tissues
Background Suicidal behaviors have become a serious public health concern globally due
to the economic and human cost of suicidal behavior to individuals, families, communities …
to the economic and human cost of suicidal behavior to individuals, families, communities …
Large epigenome-wide association study identifies multiple novel differentially methylated CpG sites associated with suicidal thoughts and behaviors in veterans
Introduction The US suicide mortality rate has steadily increased during the past two
decades, particularly among military veterans; however, the epigenetic basis of suicidal …
decades, particularly among military veterans; however, the epigenetic basis of suicidal …
Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity
Identifying cell types and brain regions critical for psychiatric disorders and brain traits is
essential for targeted neurobiological research. By integrating genomic insights from …
essential for targeted neurobiological research. By integrating genomic insights from …
High dimensional predictions of suicide risk in 4.2 million US Veterans using ensemble transfer learning
We present an ensemble transfer learning method to predict suicide from Veterans Affairs
(VA) electronic medical records (EMR). A diverse set of base models was trained to predict a …
(VA) electronic medical records (EMR). A diverse set of base models was trained to predict a …
Genome-wide methylome-based molecular pathologies associated with depression and suicide
Major depressive disorder (MDD) is a debilitating disorder. Suicide attempts are 5-times
higher in MDD patients than in the general population. Interestingly, not all MDD patients …
higher in MDD patients than in the general population. Interestingly, not all MDD patients …
A landmark federal interagency collaboration to promote data science in health care: Million Veteran Program-Computational Health Analytics for Medical Precision to …
Abstract Objectives In 2016, the Department of Veterans Affairs (VA) and the Department of
Energy (DOE) established an Interagency Agreement (IAA), the Million Veteran Program …
Energy (DOE) established an Interagency Agreement (IAA), the Million Veteran Program …
Assessment of the Genetic Characteristics of a Generation Born during a Long-Term Socioeconomic Crisis
SV Mikhailova, DE Ivanoshchuk, PS Orlov, A Bairqdar… - Genes, 2023 - mdpi.com
Background: A socioeconomic crisis in Russia lasted from 1991 to 1998 and was
accompanied by a sharp drop in the birth rate. The main factor that influenced the refusal to …
accompanied by a sharp drop in the birth rate. The main factor that influenced the refusal to …