Molecular rotors: what lies behind the high sensitivity of the thioflavin-T fluorescent marker

N Amdursky, Y Erez, D Huppert - Accounts of chemical research, 2012 - ACS Publications
Thioflavin-T (ThT) can bind to amyloid fibrils and is frequently used as a fluo-rescent marker
for in vitro biomedical assays of the potency of inhibitors for amyloid-related diseases, such …

Altered relaxation dynamics of excited state reactions by confinement in reverse micelles probed by ultrafast fluorescence up-conversion

IA Heisler, SR Meech - Chemical Society Reviews, 2021 - pubs.rsc.org
Chemical reactions in confined environments are important in areas as diverse as
heterogenous catalysis, environmental chemistry and biochemistry, yet they are much less …

Full relaxation dynamics recovery from ultrafast fluorescence experiments by means of the stochastic model: Does the solvent response dynamics depend on the …

AE Nazarov, AI Ivanov, A Rosspeintner… - Journal of Molecular …, 2022 - Elsevier
An approach to analysing time-resolved fluorescence spectra has been developed for dyes
with non-parabolic free energy curves of the excited and ground states. It incorporates the …

Ultrafast torsional dynamics of Thioflavin-T in an anionic cyclodextrin cavity

PK Singh, S Murudkar, AK Mora, S Nath - Journal of Photochemistry and …, 2015 - Elsevier
Using sub-picosecond fluorescence upconversion spectroscopy, the effect of
supramolecular confinement on the ultrafast excited state torsional dynamics of an amyloid …

Theory of fluorescence spectrum dynamics and its application to determining the relaxation characteristics of the solvent and intramolecular vibrations

RG Fedunov, IP Yermolenko, AE Nazarov… - Journal of Molecular …, 2020 - Elsevier
A general analytical expression for the transient fluorescence spectrum is derived. The
formation of a wave packet in the excited state of a fluorophore is described, assuming that …

Dynamics under confinement: torsional dynamics of Auramine O in a nanocavity

PK Singh, AK Mora, S Murudkar, S Nath - RSC advances, 2014 - pubs.rsc.org
The effect of confinement on the ultrafast torsional relaxation dynamics of a well-known
ultrafast molecular rotor (UMR) and a recently reported amyloid fibril sensor, Auramine O …

Modeling the nonradiative decay rate of electronically excited Thioflavin T

Y Erez, YH Liu, N Amdursky… - The Journal of Physical …, 2011 - ACS Publications
A computational model of nonradiative decay is developed and applied to explain the time-
dependent emission spectrum of thioflavin T (ThT). The computational model is based on a …

Basic Orange 21: a molecular rotor probe for fluorescence turn-on sensing of amyloid fibrils

SP Pandey, PK Singh - Journal of Molecular Liquids, 2020 - Elsevier
Develo** label-free fluorescence sensor for amyloid fibrils is a very important and active
field of research. Currently, there is a surge in efforts towards develo** fluorescence …

Temperature dependence of the fluorescence properties of curcumin

Y Erez, I Presiado, R Gepshtein… - The Journal of Physical …, 2011 - ACS Publications
Steady-state and time-resolved techniques were employed to study the nonradiative
process of curcumin dissolved in ethanol and 1-propanol in a wide range of temperatures …

Intramolecular charge transfer of coumarin dyes confined in methanol-in-oil reverse micelles

A Shabbir, T Jang, G Lee, Y Pang - Journal of Molecular Liquids, 2022 - Elsevier
The reverse micelles (RMs) of bis (2-ethylhexyl) sulfosuccinate sodium salt (AOT) are
considered as a model system for the molecular dynamics investigation of small …