Serotonin regulates a wide variety of brain functions and behaviors. Here, we synthesize
previous findings that serotonin regulates executive function, sensory gating, and social …

Introduction Under specific conditions, a weak lead stimulus, or “prepulse”, can inhibit the
startling effects of a subsequent intense abrupt stimulus. This startle-inhibiting effect of the …

Gender differences in schizophrenia have been extensively researched and it is being
increasingly accepted that gonadal steroids are strongly attributed to this phenomenon. Of …

The aim of the present study was to elucidate the effect of estrogen on dopaminergic and
serotonergic regulation of prepulse inhibition (PPI) by measuring its effects on the density of …

Sex differences appear to be an important factor in schizophrenia. Women with
schizophrenia tend to exhibit less disease impairment than men, typically presenting with a …

Schizophrenia is a severe psychiatric disorder with a complex and variable set of symptoms.
Both genetic and environmental mechanisms are involved in the development of the illness …

Little is known about the effects of the commonly-used oral contraceptive pill (OC) on
cognition. This study compared matched healthy women across the menstrual cycle (early …

Genetic and epigenetic factors can potentially alter susceptibility to psychiatric disorders
such as schizophrenia. In order to explore the effect of epigenetics on the pathogenesis of …

Individuals with schizophrenia (SCZ) often present sensorimotor gating impairments that can
be investigated by the prepulse inhibition test (PPI). PPI disruption can be mimicked …

Objective: This review aims to summarize the importance of animal models for research on
psychiatric illnesses, particularly schizophrenia. Method and Results: Several aspects of …