Chromosomics: Bridging the gap between genomes and chromosomes
The recent advances in DNA sequencing technology are enabling a rapid increase in the
number of genomes being sequenced. However, many fundamental questions in genome …
number of genomes being sequenced. However, many fundamental questions in genome …
Evolution of 3D Chromatin Folding
L Álvarez-González… - Annual Review of Animal …, 2024 - annualreviews.org
Studies examining the evolution of genomes have focused mainly on sequence
conservation. However, the inner working of a cell implies tightly regulated crosstalk …
conservation. However, the inner working of a cell implies tightly regulated crosstalk …
3D chromatin remodelling in the germ line modulates genome evolutionary plasticity
L Álvarez-González, F Burden, D Doddamani… - Nature …, 2022 - nature.com
Chromosome folding has profound impacts on gene regulation, whose evolutionary
consequences are far from being understood. Here we explore the relationship between 3D …
consequences are far from being understood. Here we explore the relationship between 3D …
[HTML][HTML] Principles of 3D chromosome folding and evolutionary genome reshuffling in mammals
Studying the similarities and differences in genomic interactions between species provides
fertile grounds for determining the evolutionary dynamics underpinning genome function …
fertile grounds for determining the evolutionary dynamics underpinning genome function …
Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes
Understanding the mechanisms driving lineage-specific evolution in both primates and
rodents has been hindered by the lack of sister clades with a similar phylogenetic structure …
rodents has been hindered by the lack of sister clades with a similar phylogenetic structure …
Chromosomal speciation in the genomics era: disentangling phylogenetic evolution of rock-wallabies
The association of chromosome rearrangements (CRs) with speciation is well established,
and there is a long history of theory and evidence relating to “chromosomal speciation.” …
and there is a long history of theory and evidence relating to “chromosomal speciation.” …
[PDF][PDF] Large-Scale Chromosomal Changes Lead to Genome-Level Expression Alterations, Environmental Adaptation, and Speciation in the Gayal (Bos frontalis)
Determining the functional consequences of karyotypic changes is invariably challenging
because evolution tends to obscure many of its own footprints, such as accumulated …
because evolution tends to obscure many of its own footprints, such as accumulated …
Reconstruction of the diapsid ancestral genome permits chromosome evolution tracing in avian and non-avian dinosaurs
Genomic organisation of extinct lineages can be inferred from extant chromosome-level
genome assemblies. Here, we apply bioinformatic and molecular cytogenetic approaches to …
genome assemblies. Here, we apply bioinformatic and molecular cytogenetic approaches to …
Long noncoding RNAs in ubiquitination, protein degradation, and human diseases
Protein stability and turnover is critical in normal cellular and physiological process and their
misregulation may contribute to accumulation of unwanted proteins causing cellular …
misregulation may contribute to accumulation of unwanted proteins causing cellular …
A bird's-eye view of chromosomic evolution in the class Aves
Birds (Aves) are the most speciose of terrestrial vertebrates, displaying Class-specific
characteristics yet incredible external phenotypic diversity. Critical to agriculture and as …
characteristics yet incredible external phenotypic diversity. Critical to agriculture and as …