The survival of vertebrate organisms depends on highly regulated delivery of oxygen and
nutrients through vascular networks that pervade nearly all tissues in the body …

Biology of Vascular Endothelial Growth Factor | Endocrine Reviews | Oxford Academic Skip to
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Hypoxia-inducible factor 1 (HIF-1) is found in mammalian cells cultured under reduced O2
tension and is necessary for transcriptional activation mediated by the erythropoietin gene …

Expression of vascular endothelial growth factor (VEGF) is induced in cells exposed to
hypoxia or ischemia. Neovascularization stimulated by VEGF occurs in several important …

Vascular endothelial growth factor (VEGF) is a homodimeric glycoprotein with a molecular
weight of approximately 45 kDa. It is the key mediator of angiogenesis (the formation of new …

The transcriptional response to lowered oxygen levels is mediated by the hypoxia‐inducible
transcription factor (HIF‐1), a heterodimer consisting of the constitutively expressed aryl …

Rationale: Multiple biological mechanisms contribute to the efficacy of cardiac cell therapy.
Most prominent among these are direct heart muscle and blood vessel regeneration from …

1. From avascular to vascular It is clear that for vasculogenesis and angiogenesis to
effectively proceed during physiological and pathological From the earliest stages, the …

We have isolated and characterized a cDNA for a novel Per-Arnt/AhR-Sim basic helix–loop–
helix (bHLH-PAS) factor that interacts with the Ah receptor nuclear translocator (Arnt), and its …

Vascular endothelial growth factor (VEGF) is a fundamental regulator of normal and
abnormal angiogenesis. Recent evidence indicates that VEGF is essential for embryonic …