Biogenesis and function of ESCRT-dependent extracellular vesicles

T Juan, M Fürthauer - Seminars in cell & developmental biology, 2018 - Elsevier
From bacteria to humans, cells secrete a large variety of membrane-bound extracellular
vesicles. Only relatively recently has it however started to become clear that the exovesicular …

[HTML][HTML] Helminth extracellular vesicles: Interactions with the host immune system

C Drurey, RM Maizels - Molecular Immunology, 2021 - Elsevier
As long-lived parasites, helminths depend upon immunomodulation of their hosts for
survival. The release of excretory-secretory (ES) products, including proteins, lipids and …

Extracellular vesicles from a helminth parasite suppress macrophage activation and constitute an effective vaccine for protective immunity

G Coakley, JL McCaskill, JG Borger, F Simbari… - Cell reports, 2017 - cell.com
Recent studies have demonstrated that many parasites release extracellular vesicles (EVs),
yet little is known about the specific interactions of EVs with immune cells or their functions …

A prospective view of animal and human Fasciolosis

K Cwiklinski, SM O'neill, S Donnelly… - Parasite …, 2016 - Wiley Online Library
Fasciolosis, a food‐borne trematodiasis, results following infection with the parasites,
Fasciola hepatica and Fasciola gigantica. These trematodes greatly affect the global …

Extracellular vesicle-mediated communication within host-parasite interactions

Z Wu, L Wang, J Li, L Wang, Z Wu, X Sun - Frontiers in immunology, 2019 - frontiersin.org
Extracellular vesicles (EVs) are small membrane-surrounded structures released by different
kinds of cells (normal, diseased, and transformed cells) in vivo and in vitro that contain large …

Guidelines for the purification and characterization of extracellular vesicles of parasites

C Fernandez‐Becerra, P Xander… - Journal of …, 2023 - Wiley Online Library
Parasites are responsible for the most neglected tropical diseases, affecting over a billion
people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible …

Overview of extracellular vesicle characterization techniques and introduction to combined reflectance and fluorescence confocal microscopy to distinguish …

C Bağcı, M Sever-Bahcekapili, N Belder… - …, 2022 - spiedigitallibrary.org
Extracellular vesicles (EVs) are nanoparticles (30 to 1000 nm in diameter) surrounded by a
lipid-bilayer which carry bioactive molecules between local and distal cells and participate in …

Immunomodulation by helminths: intracellular pathways and extracellular vesicles

A Zakeri, EP Hansen, SD Andersen… - Frontiers in …, 2018 - frontiersin.org
Helminth parasites are masters at manipulating host immune responses, using an array of
sophisticated mechanisms. One of the major mechanisms enabling helminths to establish …

Exploration of extracellular vesicles from Ascaris suum provides evidence of parasite–host cross talk

EP Hansen, B Fromm, SD Andersen… - Journal of …, 2019 - Taylor & Francis
The prevalent porcine helminth, Ascaris suum, compromises pig health and reduces farm
productivity worldwide. The closely related human parasite, A. lumbricoides, infects more …

[HTML][HTML] The protein and microRNA cargo of extracellular vesicles from parasitic helminths–current status and research priorities

J Sotillo, MW Robinson, MJ Kimber, M Cucher… - International journal for …, 2020 - Elsevier
Helminth parasites have a remarkable ability to persist within their mammalian hosts, which
is largely due to their secretion of molecules with immunomodulatory properties. Although …