Nanozymes: definition, activity, and mechanisms
Abstract “Nanozyme” is used to describe various catalysts from immobilized inorganic metal
complexes, immobilized enzymes to inorganic nanoparticles. Here, the history of …
complexes, immobilized enzymes to inorganic nanoparticles. Here, the history of …
Biomimetic and bioorthogonal nanozymes for biomedical applications
Nanozymes mimic the function of enzymes, which drive essential intracellular chemical
reactions that govern biological processes. They efficiently generate or degrade specific …
reactions that govern biological processes. They efficiently generate or degrade specific …
Modular Fabrication of Bioorthogonal Nanozymes for Biomedical Applications
The incorporation of transition metal catalysts (TMCs) into nanoscaffolds generates
nanocatalysts that replicate key aspects of enzymatic behavior. The TMCs can access …
nanocatalysts that replicate key aspects of enzymatic behavior. The TMCs can access …
Amphiphilic polymeric nanoparticles enable homogenous rhodium-catalysed NH insertion reactions in living cells
A Sathyan, T Loman, L Deng, ARA Palmans - Nanoscale, 2023 - pubs.rsc.org
Rh-catalysed NH carbene insertion reactions were exported to living cells with help of
amphiphilic polymeric nanoparticles. Hereto, hydrophobic dirhodium carboxylate catalysts …
amphiphilic polymeric nanoparticles. Hereto, hydrophobic dirhodium carboxylate catalysts …
Modulation of Gold Nanoparticle Ligand Structure–Dynamic Relationships Probed Using Solution NMR
Ligand dynamics plays a critical role in the chemical and biological properties of gold
nanoparticles (AuNPs). In this study, ligands featuring hydrophobic alkanethiol interiors and …
nanoparticles (AuNPs). In this study, ligands featuring hydrophobic alkanethiol interiors and …
Biodegradable Antibacterial Bioorthogonal Polymeric Nanocatalysts Prepared by Flash Nanoprecipitation
Bioorthogonal activation of pro-dyes and prodrugs using transition-metal catalysts (TMCs)
provides a promising strategy for imaging and therapeutic applications. TMCs can be loaded …
provides a promising strategy for imaging and therapeutic applications. TMCs can be loaded …
NIR-II light-activated and Cu nanocatalyst-enabled bioorthogonal reaction in living systems for efficient tumor therapy
H Huang, W Xuan, J Hai, X Wang, M Chen, G Hong… - Nano Today, 2024 - Elsevier
Bioorthogonal reaction refers to chemical reactions that occur within a biological system
without interfering the normal biochemical process, offering the unprecedented versatility in …
without interfering the normal biochemical process, offering the unprecedented versatility in …
Controlled bioorthogonal catalyst self-assembly and activity using rationally designed polymer scaffolds
Polymer-based nanocatalysts have been extensively utilized in advanced drug delivery due
to their versatility and high reactivity. Incorporating bioorthogonal transition metal catalysts …
to their versatility and high reactivity. Incorporating bioorthogonal transition metal catalysts …
Engineering of bioorthogonal polyzymes through polymer sidechain design
CM Hirschbiegel, R Goswami… - Journal of Polymer …, 2024 - Wiley Online Library
Synthetic polymer scaffolds can encapsulate transition metal catalysts (TMCs) to provide
bioorthogonal nanocatalysts. These “polyzymes” catalyze the in situ generation of …
bioorthogonal nanocatalysts. These “polyzymes” catalyze the in situ generation of …
Nanozymes for Emerging Therapy
Bioorthogonal catalysts facilitate non-native chemical reactions without disrupting inherent
biological processes. Transition metal catalysts (TMCs) mediate bioorthogonal catalysis …
biological processes. Transition metal catalysts (TMCs) mediate bioorthogonal catalysis …