Advances in technology have allowed for the sensitive, specific, and simultaneous
quantitative profiling of steroid precursors, bioactive steroids and inactive metabolites …

Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …

Membrane proteins are involved in numerous vital biological processes, including transport,
signal transduction and the enzymes in a variety of metabolic pathways. Integral membrane …

Many oxidation–reduction (redox) enzymes, particularly oxygenases, have roles in reactions
that make and break C–C bonds. The list includes cytochrome P450 and other heme-based …

The cytochrome P450 (CYP) AspB is involved in the biosynthesis of the diketopiperazine
(DKP) aspergilazine A. Tryptophan-linked dimeric DKP alkaloids are a large family of natural …

Abstract The cytochrome P450 (P450) enzymes first attracted interest because of their
relevance to the metabolism of drugs, steroids, and carcinogens. Collectively, the 57 human …

The mechanism of catalytic hydrogenation of acetophenone by the chiral complex trans-
[RuCl2 {(S)-binap}{(S, S)-dpen}] and KO-t-C4H9 in propan-2-ol is revised on the basis of …

The cytochrome P450 (CYP) superfamily of heme monooxygenases has demonstrated
ability to facilitate hydroxylation, desaturation, sulfoxidation, epoxidation, heteroatom …

The human cytochrome P450 17A1 (CYP17A1) enzyme operates at a key juncture of human
steroidogenesis, controlling the levels of mineralocorticoids influencing blood pressure …

Historically, the main barrier to membrane protein investigations has been the tendency of
membrane proteins to aggregate (due to their hydrophobic nature), in aqueous solution as …