Muscarine, imidazole, oxazole and thiazole alkaloids
Z ** - Natural product reports, 2016 - pubs.rsc.org
Covering: July 2012 to June 2015. Previous review: Nat. Prod. Rep., 2013, 30, 869–915 The
structurally diverse imidazole-, oxazole-, and thiazole-containing secondary metabolites are …
structurally diverse imidazole-, oxazole-, and thiazole-containing secondary metabolites are …
Natural cyclopeptides as anticancer agents in the last 20 years
JN Zhang, YX **a, HJ Zhang - International Journal of Molecular Sciences, 2021 - mdpi.com
Cyclopeptides or cyclic peptides are polypeptides formed by ring closing of terminal amino
acids. A large number of natural cyclopeptides have been reported to be highly effective …
acids. A large number of natural cyclopeptides have been reported to be highly effective …
Solid Phase versus Solution Phase Synthesis of Heterocyclic Macrocycles
Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic
natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior …
natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior …
Total synthesis and biological activity of natural product urukthapelstatin A
CC Lin, W Tantisantisom, SR McAlpine - Organic letters, 2013 - ACS Publications
Herein we report the first total synthesis of the natural product Urkuthaplestatin A (Ustat A)
utilizing a convergent synthetic strategy. The characterization and biological activity match …
utilizing a convergent synthetic strategy. The characterization and biological activity match …
Chiral thiazoline and thiazole building blocks for the synthesis of peptide-derived natural products
Thiazoline and thiazole heterocycles are privileged motifs found in numerous peptide-
derived natural products of biological interest. During the last decades, the synthesis of …
derived natural products of biological interest. During the last decades, the synthesis of …
Cysteine-free intramolecular ligation of N-sulfanylethylanilide peptide using 4-mercaptobenzylphosphonic acid: synthesis of cyclic peptide trichamide
An N-sulfanylethylanilide (SEAlide)-based ligation was developed for the preparation of
trichamide, a thiazole-containing cyclic peptide isolated from bloom-forming cyanobacterium …
trichamide, a thiazole-containing cyclic peptide isolated from bloom-forming cyanobacterium …
Directed production of aurantizolicin and new members based on a YM-216391 biosynthetic system
ZF Pei, MJ Yang, L Li, XH Jian, Y Yin, D Li… - Organic & …, 2018 - pubs.rsc.org
Using a highly effective heterologous expression system, the YM-216391 (1) biosynthetic
gene cluster was engineered to yield aurantizolicin (2) and the hybrid compound 3. Both of …
gene cluster was engineered to yield aurantizolicin (2) and the hybrid compound 3. Both of …
A structure–activity relationship study on multi-heterocyclic molecules: two linked thiazoles are required for cytotoxic activity
We report the synthesis, cytotoxicity, and phenotypic analysis of oxazole and thiazole
containing fragments. Evaluating the optimal size and heterocycle for growth inhibition and …
containing fragments. Evaluating the optimal size and heterocycle for growth inhibition and …
Design, synthesis and anticancer mechanistic studies of linked azoles
Herein we report the synthesis and biological activity evaluation of 2, 4 linked azole-
containing molecules. A total of 13 linked thiazole-and oxazole-containing compounds were …
containing molecules. A total of 13 linked thiazole-and oxazole-containing compounds were …
Five-Membered Ring Systems: With O and N Atoms
FM Cordero, D Giomi, L Lascialfari - Progress in Heterocyclic Chemistry, 2013 - Elsevier
Five-Membered Ring Systems: With O and N Atoms - ScienceDirect Skip to main contentSkip
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