Computational modeling (CM) is a versatile scientific methodology used to examine the
properties and behavior of complex systems, such as polymeric materials for biomedical …

The π–cation interaction that differs from the cation− π interaction is a valuable concept in
molecular design of pharmaceuticals and pesticides. In this Perspective we present an up-to …

Tetrahydro-4 H-pyrrolo [3, 2-c] quinolin-4-ones and dihydro-1 H-benzo [b] azepines are
efficiently synthesized from 2-aminobenzonitriles and donor–acceptor cyclopropanes …

The G-protein coupled estrogen receptor 1 GPER/GPR30 is a transmembrane seven-helix
(7TM) receptor involved in the growth and proliferation of breast cancer. Due to the absence …

The combination of Ichikawa's rearrangement and a ring-closing metathesis reaction of allyl
carbamates is presented as a method for the preparation of 5-amino-substituted 2, 5-dihydro …

Adenosine receptors (ARs) belong to family A of GPCRs that are involved in many diseases,
including cerebral and cardiac ischemic diseases, immune and inflammatory disorders, etc …

Regulating mechanisms of fibrosis is an important goal in the treatment of fibrosis and liver
cirrhosis. The role of arginine vasopressin (AVP) in promoting fibrosis in several organs has …

US11505558B1 - Antiviral heterocyclic compounds - Google Patents US11505558B1 - Antiviral
heterocyclic compounds - Google Patents Antiviral heterocyclic compounds Download PDF …

The computational strategies permeate all aspects of drug discovery such as virtual
screening techniques. Virtual screening can be classified into ligand based and structure …

Arginine vasopressin (AVP) has been recently recognized as an immunoregulatory
hormone. Here we summarize the most representative experiments and discuss results …