Molecular landscape of recurrent cervical cancer

D Adiga, S Eswaran, D Pandey, K Sharan… - Critical Reviews in …, 2021 - Elsevier
Cervical cancer (CC) is a major gynecological problem in develo** and underdeveloped
countries. Despite the significant advancement in early detection and treatment modalities …

Signaling pathways in HPV‐associated cancers and therapeutic implications

J Chen - Reviews in medical virology, 2015 - Wiley Online Library
Human papillomaviruses (HPVs) are small double‐stranded circular DNA viruses with 8 kb
genomes. So far, more than 150 HPVs have been identified, and 12 types of HPVs have …

Oncogenic mutations in cervical cancer: genomic differences between adenocarcinomas and squamous cell carcinomas of the cervix

AA Wright, BE Howitt, AP Myers, SE Dahlberg… - Cancer, 2013 - Wiley Online Library
BACKGROUND Cervical cancer is the second leading cause of cancer deaths among
women worldwide. The objective of this study was to describe the most common oncogenic …

Somatic host cell alterations in HPV carcinogenesis

TR Litwin, MA Clarke, M Dean, N Wentzensen - Viruses, 2017 - mdpi.com
High-risk human papilloma virus (HPV) infections cause cancers in different organ sites,
most commonly cervical and head and neck cancers. While carcinogenesis is initiated by …

Clinical perspectives of cancer stem cell research in radiation oncology

R Bütof, A Dubrovska, M Baumann - Radiotherapy and oncology, 2013 - Elsevier
Radiotherapy has a proven potential to eradicate cancer stem cells which is reflected by its
curative potential in many cancer types. Considerable progress has been made in …

Tissue biomarkers as prognostic variables of cervical cancer

A Gadducci, ME Guerrieri, C Greco - Critical reviews in oncology …, 2013 - Elsevier
The most important prognostic variables of cervical carcinoma are FIGO stage, lymph node
status and clinical-pathological features of primary tumor. Recently, there has been …

[HTML][HTML] Biological significance and therapeutic implication of resveratrol-inhibited Wnt, Notch and STAT3 signaling in cervical cancer cells

P Zhang, H Li, B Yang, F Yang, LL Zhang… - Genes & …, 2014 - ncbi.nlm.nih.gov
Cervical cancers/CCs are one of the commonest malignancies and the second leading
cause of cancer-related death in women. Resveratrol inhibits CC cell growth but its …

Role of cytokines in genesis, progression and prognosis of cervical cancer

PH Paradkar, JV Joshi, PN Mertia… - Asian Pacific journal …, 2014 - koreascience.kr
Cytokine research is currently at the forefront in cancer research. Deciphering the functions
of these multiple small molecules, discovered within the cell and in intercellular spaces, with …

Defucosylated Anti-Epidermal Growth Factor Receptor Monoclonal Antibody 134-mG2a-f Exerts Antitumor Activities in Mouse Xenograft Models of Dog Epidermal …

N Tateyama, R Nanamiya, T Ohishi, J Takei… - Monoclonal …, 2021 - liebertpub.com
The epidermal growth factor receptor (EGFR) is a type I transmembrane protein, which is a
member of the human epidermal growth factor receptor (HER) family of receptor tyrosine …

E6 Protein Expressed by High-Risk HPV Activates Super-Enhancers of the EGFR and c-MET Oncogenes by Destabilizing the Histone Demethylase KDM5C

X Chen, JX Loo, X Shi, W **ong, Y Guo, H Ke, M Yang… - Cancer research, 2018 - AACR
The high-risk (HR) human papillomaviruses (HPV) are causative agents of anogenital tract
dysplasia and cancers and a fraction of head and neck cancers. The HR HPV E6 …