Proteomic analysis of post-translational modifications
Post-translational modifications modulate the activity of most eukaryote proteins. Analysis of
these modifications presents formidable challenges but their determination generates …
these modifications presents formidable challenges but their determination generates …
Modification-specific proteomics: characterization of post-translational modifications by mass spectrometry
ON Jensen - Current opinion in chemical biology, 2004 - Elsevier
Post-translational modifications generate tremendous diversity, complexity and
heterogeneity of gene products, and their determination is one of the main challenges in …
heterogeneity of gene products, and their determination is one of the main challenges in …
Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry
JEP Syka, JJ Coon, MJ Schroeder… - Proceedings of the …, 2004 - National Acad Sciences
Peptide sequence analysis using a combination of gas-phase ion/ion chemistry and tandem
mass spectrometry (MS/MS) is demonstrated. Singly charged anthracene anions transfer an …
mass spectrometry (MS/MS) is demonstrated. Singly charged anthracene anions transfer an …
Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome
In signal transduction in eukaryotes, protein phosphorylation is a key event. To understand
signaling processes, we must first acquire an inventory of phosphoproteins and their …
signaling processes, we must first acquire an inventory of phosphoproteins and their …
Interpreting the protein language using proteomics
ON Jensen - Nature reviews Molecular cell biology, 2006 - nature.com
Post-translational modifications define the functional and structural plasticity of proteins in
archaea, prokaryotes and eukaryotes. Multi-site protein modification modulates protein …
archaea, prokaryotes and eukaryotes. Multi-site protein modification modulates protein …
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway* S
Cellular processes such as proliferation, differentiation, and adaptation to environmental
changes are regulated by protein phosphorylation. Development of sensitive and …
changes are regulated by protein phosphorylation. Development of sensitive and …
On the development of plasma protein biomarkers
The development of plasma biomarkers has proven to be more challenging than initially
anticipated. Many studies have reported lists of candidate proteins rather than validated …
anticipated. Many studies have reported lists of candidate proteins rather than validated …
Current and prospective applications of metal ion–protein binding
Since immobilized metal ion affinity chromatography (IMAC) was first introduced, several
variants of this method and many other metal affinity-based techniques have been devised …
variants of this method and many other metal affinity-based techniques have been devised …
Post-translational modifications and their biological functions: proteomic analysis and systematic approaches
JW Seo, KJ Lee - BMB Reports, 2004 - koreascience.kr
Recently produced information on post-translational modifications makes it possible to
interpret their biological regulation with new insights. Various protein modifications finely …
interpret their biological regulation with new insights. Various protein modifications finely …
Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications* S
We developed novel methods for phosphopeptide enrichment using aliphatic hydroxy acid-
modified metal oxide chromatography (MOC). Titania and zirconia were successfully applied …
modified metal oxide chromatography (MOC). Titania and zirconia were successfully applied …