Stress, glucocorticoids and memory: implications for treating fear-related disorders

D de Quervain, L Schwabe… - Nature Reviews …, 2017 - nature.com
Glucocorticoid stress hormones are crucially involved in modulating mnemonic processing
of emotionally arousing experiences. They enhance the consolidation of new memories …

Gene–stress–epigenetic regulation of FKBP5: clinical and translational implications

AS Zannas, T Wiechmann, NC Gassen… - …, 2016 - nature.com
Stress responses and related outcomes vary markedly across individuals. Elucidating the
molecular underpinnings of this variability is of great relevance for develo** individualized …

The hypothalamic-pituitary-adrenal axis in PTSD: Pathophysiology and treatment interventions

BW Dunlop, A Wong - Progress in Neuro-psychopharmacology and …, 2019 - Elsevier
Questions of how altered functioning of the hypothalamic pituitary adrenal (HPA) axis
contribute to the development and maintenance of posttraumatic stress disorder (PTSD) …

The centrality of fear extinction in linking risk factors to PTSD: A narrative review

DV Zuj, MA Palmer, MJJ Lommen… - … & Biobehavioral Reviews, 2016 - Elsevier
Recent prospective studies in emergency services have identified impaired fear extinction
learning and memory to be a significant predictor of Posttraumatic Stress Disorder (PTSD) …

Vantage sensitivity: Environmental sensitivity to positive experiences as a function of genetic differences

M Pluess - Journal of personality, 2017 - Wiley Online Library
A large number of gene–environment interaction studies provide evidence that some people
are more likely to be negatively affected by adverse experiences as a function of specific …

HPA axis related genes and response to psychological therapies: genetics and epigenetics

S Roberts, R Keers, KJ Lester… - Depression and …, 2015 - Wiley Online Library
Background Hypothalamic–pituitary–adrenal (HPA) axis functioning has been implicated in
the development of stress‐related psychiatric diagnoses and response to adverse life …

Oxytocin pathways in the intergenerational transmission of maternal early life stress

P Toepfer, C Heim, S Entringer, E Binder… - Neuroscience & …, 2017 - Elsevier
Severe stress in early life, such as childhood abuse and neglect, constitutes a major risk
factor in the etiology of psychiatric disorders and somatic diseases. Importantly, these long …

Glucocorticoid-induced enhancement of extinction—from animal models to clinical trials

D de Quervain, OT Wolf, B Roozendaal - Psychopharmacology, 2019 - Springer
Extensive evidence from both animal model and human research indicates that
glucocorticoid hormones are crucially involved in modulating memory performance …

Biological underpinnings of trauma and post-traumatic stress disorder: focusing on genetics and epigenetics

J Ryan, I Chaudieu, ML Ancelin, R Saffery - Epigenomics, 2016 - Taylor & Francis
Certain individuals are more susceptible to stress and trauma, as well as the physical and
mental health consequences following such exposure, including risk for post-traumatic …

Genetics of glucocorticoid regulation and posttraumatic stress disorder—what do we know?

I Castro-Vale, EFC van Rossum, JC Machado… - Neuroscience & …, 2016 - Elsevier
Abstract CASTRO-VALE, I., EFC van Rossum, JC Machado, R. Mota-Cardoso and D.
Carvalho. Genetics of glucocorticoid regulation and posttraumatic stress disorder—What do …