The role of the VEGF family in coronary heart disease

Y Zhou, X Zhu, H Cui, J Shi, G Yuan, S Shi… - Frontiers in …, 2021‏ - frontiersin.org
The vascular endothelial growth factor (VEGF) family, the regulator of blood and lymphatic
vessels, is mostly investigated in the tumor and ophthalmic field. However, the functions it …

[HTML][HTML] Diet, inflammation and the gut microbiome: Mechanisms for obesity-associated cognitive impairment

SJ Leigh, MJ Morris - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2020‏ - Elsevier
Poor diet and obesity are associated with cognitive impairment throughout adulthood, and
increased dementia risk in aging. Here we review the current literature interrogating the …

Obesity-induced blood-brain barrier dysfunction: phenotypes and mechanisms

Z Feng, C Fang, Y Ma, J Chang - Journal of Neuroinflammation, 2024‏ - Springer
Obesity, a burgeoning global health issue, is increasingly recognized for its detrimental
effects on the central nervous system, particularly concerning the integrity of the blood-brain …

The role of the VEGF family in atherosclerosis development and its potential as treatment targets

SA Dabravolski, VA Khotina, AV Omelchenko… - International journal of …, 2022‏ - mdpi.com
The vascular endothelial growth factor (VEGF) family, the crucial regulator of angiogenesis,
lymphangiogenesis, lipid metabolism and inflammation, is involved in the development of …

Overnutrition induced cognitive impairment: insulin resistance, gut-brain axis, and neuroinflammation

Q Zhang, K **, B Chen, R Liu, S Cheng… - Frontiers in …, 2022‏ - frontiersin.org
Overnutrition-related obesity has become a worldwide epidemic, and its prevalence is
expected to steadily rise in the future. It is widely recognized that obesity exerts negative …

Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension

T Gruber, C Pan, RE Contreras, T Wiedemann… - Cell metabolism, 2021‏ - cell.com
Pathologies of the micro-and macrovascular systems are a hallmark of the metabolic
syndrome, which can lead to chronically elevated blood pressure. However, the underlying …

The cognitive control of eating and body weight: it's more than what you “think”

TL Davidson, S Jones, M Roy… - Frontiers in psychology, 2019‏ - frontiersin.org
Over the past decade, a great deal of research has established the importance of cognitive
processes in the control of energy intake and body weight. The present paper begins by …

Memory and eating: A bidirectional relationship implicated in obesity

MB Parent, S Higgs, LG Cheke, SE Kanoski - … & Biobehavioral Reviews, 2022‏ - Elsevier
This paper reviews evidence demonstrating a bidirectional relationship between memory
and eating in humans and rodents. In humans, amnesia is associated with impaired …

Alterations of the blood-brain barrier during aging

Y Cao, W Xu, Q Liu - Journal of Cerebral Blood Flow & …, 2024‏ - journals.sagepub.com
The blood-brain barrier (BBB) is a complex and dynamic interface that regulates the
exchange of molecules and cells between the blood and the central nervous system. It …

Decrypting the potential role of α-lipoic acid in Alzheimer's disease

D Kaur, T Behl, A Sehgal, S Singh, N Sharma… - Life Sciences, 2021‏ - Elsevier
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases with
motor disturbances, cognitive decline, and behavioral impairment. It is characterized by the …