Management of oxidative stress and other pathologies in Alzheimer's disease

M Simunkova, SH Alwasel, IM Alhazza, K Jomova… - Archives of …, 2019 - Springer
Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder, characterized by
the formation, aggregation and accumulation of amyloid beta, perturbed metal (copper, iron …

Organophosphorus compounds and oximes: a critical review

F Worek, H Thiermann, T Wille - Archives of Toxicology, 2020 - Springer
Organophosphorus (OP) pesticides and nerve agents still pose a threat to the population.
Treatment of OP poisoning is an ongoing challenge and burden for medical services …

Destruction and detection of chemical warfare agents

K Kim, OG Tsay, DA Atwood, DG Churchill - Chemical reviews, 2011 - ACS Publications
This review is shaped in scope by much and various chemical, biological, materials science,
device, and chemical engineering literature. This review is intended to make major …

<? ACS-CT-START-Insert?> Update 1 of:<? ACS-CT-END-Insert?> Destruction and Detection of Chemical Warfare Agents

… <? ACS-CT-START-Insert?> Jang<? ACS-CT … - Chemical …, 2015 - ACS Publications
Yang and co-workers appeared (Figure 1), 2 and 16 years since their accompanying
Accounts article,“Chemical Detoxification of Nerve Agent VX.” 14 Also, organophosphonate …

Organophosphorus compounds as chemical warfare agents: a review

RT Delfino, TS Ribeiro… - Journal of the Brazilian …, 2009 - SciELO Brasil
Chemical warfare agents constitute one of the greatest threats in the modern world. Among
them, the neurotoxic agents are of special interest due to their high lethality and danger …

The value of novel oximes for treatment of poisoning by organophosphorus compounds

F Worek, H Thiermann - Pharmacology & therapeutics, 2013 - Elsevier
Poisoning by organophosphorus compounds (OP) still is a major therapeutic problem.
Intentional OP pesticide poisoning results in up to 300.000 deaths each year and highly …

[CARTE][B] Chemical warfare agents: chemistry, pharmacology, toxicology, and therapeutics

BJ Lukey, JA Romano Jr, JA Romano, H Salem… - 2007 - taylorfrancis.com
The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was
published just prior to the terrorist attacks of September 11th, 2001. Reflecting a greater …

SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides

L Gorecki, J Korabecny, K Musilek, D Malinak… - Archives of …, 2016 - Springer
Irreversible inhibition of acetylcholinesterase (AChE) by organophosphates leads to many
failures in living organism and ultimately in death. Organophosphorus compounds …

Sarin (GB, O-isopropyl methylphosphonofluoridate) neurotoxicity: critical review

MB Abou-Donia, B Siracuse, N Gupta… - Critical reviews in …, 2016 - Taylor & Francis
Sarin (GB, O-isopropyl methylphosphonofluoridate) is a potent organophosphorus (OP)
nerve agent that inhibits acetylcholinesterase (AChE) irreversibly. The subsequent build-up …

Trichothecenes: Structure-toxic activity relationships

Q Wu, V Dohnal, K Kuca, Z Yuan - Current Drug Metabolism, 2013 - ingentaconnect.com
Trichothecenes comprise a large family of structurally related toxins mainly produced by
fungi belonging to the genus Fusarium. Among trichothecenes, type A and type B are of the …