Cadherin 13 in cancer

AV Andreeva, MA Kutuzov - Genes, Chromosomes and Cancer, 2010 - Wiley Online Library
We review the evidence suggesting the involvement of Cadherin 13 (CDH13, T‐cadherin, H‐
cadherin) in various cancers. CDH13 is an atypical member of the cadherin family, devoid of …

The miR-30 family: Versatile players in breast cancer

SJ Yang, SY Yang, DD Wang, X Chen… - Tumor …, 2017 - journals.sagepub.com
The microRNA family, miR-30, plays diverse roles in regulating key aspects of neoplastic
transformation, metastasis, and clinical outcomes in different types of tumors. Accumulating …

Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

YJ Cho, A Tsherniak, P Tamayo, S Santagata… - Journal of clinical …, 2011 - ascopubs.org
Purpose Medulloblastomas are heterogeneous tumors that collectively represent the most
common malignant brain tumor in children. To understand the molecular characteristics …

miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis

A Gaziel-Sovran, MF Segura, R Di Micco, MK Collins… - Cancer cell, 2011 - cell.com
To metastasize, a tumor cell must acquire abilities such as the capacity to colonize new
tissue and evade immune surveillance. Recent evidence suggests that microRNAs can …

Population differences in microRNA expression and biological implications

RS Huang, ER Gamazon, D Ziliak, Y Wen, HK Im… - RNA biology, 2011 - Taylor & Francis
Population differences observed for complex traits may be attributed to the combined effect
of socioeconomic, environmental, genetic and epigenetic factors. To better understand …

MicroRNA‐30b functions as a tumour suppressor in human colorectal cancer by targeting KRAS, PIK3CD and BCL2

WT Liao, YP Ye, NJ Zhang, TT Li… - The Journal of …, 2014 - Wiley Online Library
Colorectal cancer (CRC) is the third most common cancer in the USA. MicroRNAs play
important roles in the pathogenesis of CRC. In this study, we investigated the role of miR …

The curcumin analog EF24 targets NF-κB and miRNA-21, and has potent anticancer activity in vitro and in vivo

CH Yang, J Yue, M Sims, LM Pfeffer - PloS one, 2013 - journals.plos.org
EF24 is a curcumin analog that has improved anticancer activity over curcumin, but its
therapeutic potential and mechanism of action is unknown, which is important to address as …

MicroRNA-30d-5p inhibits tumour cell proliferation and motility by directly targeting CCNE2 in non-small cell lung cancer

DI Chen, W Guo, Z Qiu, Q Wang, Y Li, L Liang, L Liu… - Cancer letters, 2015 - Elsevier
MicroRNAs (miRNAs) are small, single-stranded, non-coding RNA molecules that are
dysregulated in many types of human cancers, although their precise functions in driving …

Miat and interacting protein Metadherin maintain a stem-like niche to promote medulloblastoma tumorigenesis and treatment resistance

KL Peng, HN Vasudevan, DT Lockney… - Proceedings of the …, 2022 - National Acad Sciences
Long noncoding RNAs (lncRNAs) play essential roles in the development and progression
of many cancers. However, the contributions of lncRNAs to medulloblastoma (MB) remain …

Ricolinostat (ACY-1215) suppresses proliferation and promotes apoptosis in esophageal squamous cell carcinoma via miR-30d/PI3K/AKT/mTOR and ERK pathways

J Cao, W Lv, L Wang, J Xu, P Yuan, S Huang… - Cell death & …, 2018 - nature.com
Abstract Ricolinostat (ACY-1215), a first-in-class selective HDAC6 inhibitor, exhibits
antitumor effects alone or in combination with other drugs in various cancers. However, its …