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Microbial evolution through horizontal gene transfer by mobile genetic elements
Mobile genetic elements (MGEs) are crucial for horizontal gene transfer (HGT) in bacteria
and facilitate their rapid evolution and adaptation. MGEs include plasmids, integrative and …
and facilitate their rapid evolution and adaptation. MGEs include plasmids, integrative and …
Genomic islands: tools of bacterial horizontal gene transfer and evolution
Bacterial genomes evolve through mutations, rearrangements or horizontal gene transfer.
Besides the core genes encoding essential metabolic functions, bacterial genomes also …
Besides the core genes encoding essential metabolic functions, bacterial genomes also …
progressiveMauve: multiple genome alignment with gene gain, loss and rearrangement
Background Multiple genome alignment remains a challenging problem. Effects of
recombination including rearrangement, segmental duplication, gain, and loss can create a …
recombination including rearrangement, segmental duplication, gain, and loss can create a …
Organised Genome Dynamics in the Escherichia coli Species Results in Highly Diverse Adaptive Paths
The Escherichia coli species represents one of the best-studied model organisms, but also
encompasses a variety of commensal and pathogenic strains that diversify by high rates of …
encompasses a variety of commensal and pathogenic strains that diversify by high rates of …
Horizontal transfer, not duplication, drives the expansion of protein families in prokaryotes
Gene duplication followed by neo-or sub-functionalization deeply impacts the evolution of
protein families and is regarded as the main source of adaptive functional novelty in …
protein families and is regarded as the main source of adaptive functional novelty in …
Inferring horizontal gene transfer
Horizontal or Lateral Gene Transfer (HGT or LGT) is the transmission of portions of genomic
DNA between organisms through a process decoupled from vertical inheritance. In the …
DNA between organisms through a process decoupled from vertical inheritance. In the …
The dynamics of gut‐associated microbial communities during inflammation
Our intestine is host to a large microbial community (microbiota) that educates the immune
system and confers niche protection. Profiling of the gut‐associated microbial community …
system and confers niche protection. Profiling of the gut‐associated microbial community …
So similar, yet so different: uncovering distinctive features in the genomes of Salmonella enterica serovars Typhimurium and Typhi
SC Sabbagh, CG Forest, C Lepage… - FEMS microbiology …, 2010 - academic.oup.com
Salmonella enterica represents a major human and animal pathogen. Many S. enterica
genomes have been completed and many more genome sequencing projects are …
genomes have been completed and many more genome sequencing projects are …
The adaptation of temperate bacteriophages to their host genomes
Rapid turnover of mobile elements drives the plasticity of bacterial genomes. Integrated
bacteriophages (prophages) encode host-adaptive traits and represent a sizable fraction of …
bacteriophages (prophages) encode host-adaptive traits and represent a sizable fraction of …
Evaluation of genomic island predictors using a comparative genomics approach
Abstract Background Genomic islands (GIs) are clusters of genes in prokaryotic genomes of
probable horizontal origin. GIs are disproportionately associated with microbial adaptations …
probable horizontal origin. GIs are disproportionately associated with microbial adaptations …