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[HTML][HTML] Exploring the role of sporadic BRAF and KRAS mutations during colorectal cancer pathogenesis: a spotlight on the contribution of the endosome-lysosome …
The highly heterogenous nature of colorectal cancer can significantly hinder its early and
accurate diagnosis, eventually contributing to high mortality rates. The adenoma-carcinoma …
accurate diagnosis, eventually contributing to high mortality rates. The adenoma-carcinoma …
Altered expression of vesicular trafficking machinery in prostate cancer affects lysosomal dynamics and provides insight into the underlying biology and disease …
Background This study focuses on the role of lysosomal trafficking in prostate cancer, given
the essential role of lysosomes in cellular homoeostasis. Methods Lysosomal motility was …
the essential role of lysosomes in cellular homoeostasis. Methods Lysosomal motility was …
Dynamic interplay between sortilin and syndecan-1 contributes to prostate cancer progression
J Lazniewska, KL Li, IRD Johnson, A Sorvina… - Scientific reports, 2023 - nature.com
Prostate cancer (PCa) development and progression relies on the programming of glucose
and lipid metabolism, and this involves alterations in androgen receptor expression and …
and lipid metabolism, and this involves alterations in androgen receptor expression and …
[HTML][HTML] Components of the Endosome-Lysosome Vesicular Machinery as Drivers of the Metastatic Cascade in Prostate Cancer
Prostate cancer remains a significant global health concern, with over 1.4 million new cases
diagnosed and more than 330,000 deaths each year. The primary clinical challenge that …
diagnosed and more than 330,000 deaths each year. The primary clinical challenge that …
Reinterpretation of prostate cancer pathology by Appl1, Sortilin and Syndecan-1 biomarkers
The diagnosis of prostate cancer using histopathology is reliant on the accurate
interpretation of prostate tissue sections. Current standards rely on the assessment of …
interpretation of prostate tissue sections. Current standards rely on the assessment of …
[HTML][HTML] Appl1, Sortilin and Syndecan-1 immunohistochemistry on intraductal carcinoma of the prostate provides evidence of retrograde spread
The presence of intraductal carcinoma of the prostate (IDCP) correlates with late-stage
disease and poor outcomes for patients with prostatic adenocarcinoma, but the accurate and …
disease and poor outcomes for patients with prostatic adenocarcinoma, but the accurate and …
[HTML][HTML] Insights into melanoma clinical practice: a perspective for future research
Simple Summary This study acknowledges the challenges in melanoma diagnosis and the
need for new technology that aids clinical decision making. Biomarkers that can accurately …
need for new technology that aids clinical decision making. Biomarkers that can accurately …
Distinct patterns of biomarker expression for atypical intraductal proliferations in prostate cancer
High-grade prostatic intraepithelial neoplasia (HGPIN) is a well-characterised precursor
lesion in prostate cancer. The term atypical intraductal proliferations (AIP) describes lesions …
lesion in prostate cancer. The term atypical intraductal proliferations (AIP) describes lesions …
[HTML][HTML] In Advanced Prostate Cancer, a String of Modest Gains Are Changing Patient Care
J Kaltwasser - 2023 - targetedonc.com
In Advanced Prostate Cancer, a String of Modest Gains Are Changing Patient Care NEWS All
NewsFDA BriefsOncology IconsSpecial ReportsThe Targeted PulseVoices from the Field …
NewsFDA BriefsOncology IconsSpecial ReportsThe Targeted PulseVoices from the Field …