Sleep and epilepsy: A snapshot of knowledge and future research lines

L Nobili, B Frauscher, S Eriksson… - Journal of sleep …, 2022 - Wiley Online Library
Sleep and epilepsy have a reciprocal relationship, and have been recognized as bedfellows
since antiquity. However, research on this topic has made a big step forward only in recent …

Seizure forecasting: bifurcations in the long and winding road

MO Baud, T Proix, NM Gregg, BH Brinkmann… - …, 2023 - Wiley Online Library
To date, the unpredictability of seizures remains a source of suffering for people with
epilepsy, motivating decades of research into methods to forecast seizures. Originally, only …

Seizure forecasting using a novel sub-scalp ultra-long term EEG monitoring system

RE Stirling, MI Maturana, PJ Karoly, ES Nurse… - Frontiers in …, 2021 - frontiersin.org
Accurate identification of seizure activity, both clinical and subclinical, has important
implications in the management of epilepsy. Accurate recognition of seizure activity is …

Thalamic deep brain stimulation modulates cycles of seizure risk in epilepsy

NM Gregg, V Sladky, P Nejedly, F Mivalt, I Kim… - Scientific reports, 2021 - nature.com
Chronic brain recordings suggest that seizure risk is not uniform, but rather varies
systematically relative to daily (circadian) and multiday (multidien) cycles. Here, one human …

SleepSEEG: automatic sleep scoring using intracranial EEG recordings only

N von Ellenrieder, L Peter-Derex… - Journal of Neural …, 2022 - iopscience.iop.org
Objective. To perform automatic sleep scoring based only on intracranial
electroencephalography (iEEG), without the need for scalp EEG), electrooculography (EOG) …

Putative roles for homeostatic plasticity in epileptogenesis

NP Issa, KC Nunn, S Wu, HA Haider, JX Tao - Epilepsia, 2023 - Wiley Online Library
Homeostatic plasticity allows neural circuits to maintain an average activity level while
preserving the ability to learn new associations and efficiently transmit information. This …

Electrical brain stimulation and continuous behavioral state tracking in ambulatory humans

F Mivalt, V Kremen, V Sladky, I Balzekas… - Journal of neural …, 2022 - iopscience.iop.org
Objective. Electrical deep brain stimulation (DBS) is an established treatment for patients
with drug-resistant epilepsy. Sleep disorders are common in people with epilepsy, and DBS …

The relationship between sleep, epilepsy, and development: a review

AH Roliz, S Kothare - Current Neurology and Neuroscience Reports, 2023 - Springer
Abstract Purpose of Review To review the relationship between sleep, neurodevelopment,
and epilepsy and potential underlying physiological mechanisms. Recent Findings Recent …

Asymmetry of sleep electrophysiological markers in patients with focal epilepsy

L Sheybani, P Mégevand, N Roehri… - Brain …, 2023 - academic.oup.com
Sleep can modulate epileptic activities, but our knowledge of sleep perturbation by epilepsy
remains sparse. Interestingly, epilepsy and sleep both present with defining …

Sleep and seizure risk in epilepsy: bed and wake times are more important than sleep duration

RE Stirling, CM Hidajat, DB Grayden, WJ D'Souza… - Brain, 2023 - academic.oup.com
Sleep duration, sleep deprivation and the sleep–wake cycle are thought to play an important
role in the generation of epileptic activity and may also influence seizure risk. Hence, people …