Nitrile metabolizing enzymes, ie, aldoxime dehydratase, hydroxynitrile lyase, nitrilase, nitrile
hydratase, and amidase, are the key catalysts in carbon nitrogen triple bond anabolism and …

In the present work, a convenient and straightforward approach to the preparation of
borylated amidines based on the closo-dodecaborate anion [B12H11NCCH3NHR]−, R= H …

Background: Terpenoids are hydrocarbon compounds derived from common five-carbon
isoprene (C5H8) building blocks. They are formed through the condensation and …

Taxol®(paclitaxel) has fascinated researchers, medical professionals, politicians and
entrepreneurs for almost half a century. Its medicinal value as a potent anti-cancer …

Ethnopharmacological relevance The flowering tops of Trifolium pratense L., popularly
known as red clover, are used in ethnic Western and Traditional Chinese medicine, in a …

Abstract The Morita‐Baylis‐Hillman (MBH) reaction affords highly functionalised allylic
alcohols containing a new stereogenic centre. These MBH adducts are very versatile and …

Nitriles are abundant in the plant kingdom. The ability to detoxify them is beneficial for
microbes living in the plant environment. Nitrilases (NLases; EC 3.5. 5.-), which hydrolyze …

A novel and convenient method for the synthesis of β, γ-unsaturated nitriles using ACCN (1,
1′-azobis (cyclohexane-1-carbonitrile)) as a cyano source was described. This reaction …

Nitrilases are the enzymes that catalyze the hydrolysis of nitriles to corresponding carboxylic
acid and ammonia. They are broadly categorized into aromatic, aliphatic, and …

Nitrile hydratase (NHase) has attracted considerable attention since it can efficiently
catalyze the hydration of nitriles to valuable amides. However, the poor stability of NHase is …