Background Development of efficient strategies has always been one of the great
perspectives for biotechnologists. During the last decade, genome editing of different …

Early detection of viral pathogens by DNA-sensors in clinical samples, contaminated foods,
soil or water can dramatically improve clinical outcomes and reduce the socioeconomic …

Background Genome of an organism has always fascinated life scientists. With the discovery
of restriction endonucleases, scientists were able to make targeted manipulations …

Zebrafish (Danio rerio) is a valuable non-mammalian vertebrate model widely used to study
development and disease, including more recently cancer. The evolutionary conservation of …

The widespread use of Cas12a (formerly Cpf1) nucleases for genome engineering is limited
by their requirement for a rather long TTTV protospacer adjacent motif (PAM) sequence …

The class II clustered regularly interspaced short palindromic repeats (CRISPR)–Cas
systems, characterized by a single effector protein, can be further subdivided into types II, V …

In insects, odorant receptors facilitate olfactory communication and require the functionality
of the highly conserved co-receptor gene orco. Genome editing studies in a few species of …

Gene editing techniques, which help in modification of any DNA sequence at ease, have
revolutionized the world of Genetic engineering. Although there are other gene-editing …

With the rising global demand for seafood and the challenges posed by overfishing and
climate change, the aquaculture sector has become increasingly important in providing high …

Phytophthora infestans is a destructive pathogen of potato and a model for investigations of
oomycete biology. The successful application of a CRISPR gene editing system to P …