Cardiac rehabilitation for heart failure:'Cinderella'or evidence-based pillar of care?

RS Taylor, HM Dalal, AD Zwisler - European heart journal, 2023 - academic.oup.com
Cardiac rehabilitation remains the 'Cinderella'of treatments for heart failure. This state-of-the-
art review provides a contemporary update on the evidence base, clinical guidance, and …

Molecular mechanisms of exercise contributing to tissue regeneration

J Chen, R Zhou, Y Feng, L Cheng - Signal Transduction and Targeted …, 2022 - nature.com
Physical activity has been known as an essential element to promote human health for
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …

Efficacy and safety of dapagliflozin according to frailty in patients with heart failure: a prespecified analysis of the DELIVER trial

JH Butt, PS Jhund, J Belohlávek, RA De Boer… - Circulation, 2022 - Am Heart Assoc
Background: Frailty is increasing in prevalence. Because patients with frailty are often
perceived to have a less favorable risk/benefit profile, they may be less likely to receive new …

Frailty and heart failure: State‐of‐the‐art review

KM Talha, A Pandey, M Fudim, J Butler… - Journal of Cachexia …, 2023 - Wiley Online Library
At least half of all patients with heart failure (HF) are affected by frailty, a syndrome that limits
an individual ability to recover from acute stressors. While frailty affects up to 90% of patients …

Frailty and effects of a multidomain physical rehabilitation intervention among older patients hospitalized for acute heart failure: a secondary analysis of a randomized …

A Pandey, DW Kitzman, MB Nelson, AM Pastva… - JAMA …, 2023 - jamanetwork.com
Importance Frailty is common among older patients with acute decompensated heart failure
(ADHF) and is associated with worse quality of life (QOL) and a higher risk of clinical events …

Patterns of referral and postdischarge utilization of cardiac rehabilitation among patients hospitalized with heart failure: an analysis from the GWTG-HF Registry

N Keshvani, V Subramanian, CA Wrobel… - Circulation: Heart …, 2023 - Am Heart Assoc
BACKGROUND: Coverage for cardiac rehabilitation (CR) for patients with heart failure with
reduced ejection fraction was expanded in 2014, but contemporary referral and participation …

Frailty status modifies the efficacy of ICD therapy for primary prevention among patients with HF

MW Segar, N Keshvani, S Singh, L Patel, S Parsa… - Heart Failure, 2024 - jacc.org
Background Implantable cardioverter-defibrillator (ICD) therapy is recommended to reduce
mortality risk in patients with heart failure with reduced ejection fraction (HFrEF). Frailty is …

Frailty and cardiovascular mortality: a narrative review

D Ko, JA Bostrom, S Qazi, DB Kramer, DH Kim… - Current cardiology …, 2023 - Springer
Abstract Purpose of Review The goal of the narrative review is to provide an overview of the
epidemiology of frailty in cardiovascular disease and cardiovascular mortality and discuss …

Assessing and managing frailty in advanced heart failure: An International Society for Heart and Lung Transplantation consensus statement

QE Denfeld, SR Jha, E Fung, T Jaarsma… - The Journal of Heart and …, 2024 - Elsevier
Frailty is increasingly recognized as a salient condition in patients with heart failure (HF) as
previous studies have determined that frailty is highly prevalent and prognostically …

Distinct impact of noncardiac comorbidities on exercise capacity and functional status in chronic heart failure

P Martens, SN Augusto Jr, JE Finet, WHW Tang - Heart Failure, 2023 - jacc.org
Abstract Background Noncardiac comorbidities (NCCs) are common in patients with heart
failure (HF), but how they jointly affect exercise capacity and functional status is relatively …