State‐of‐the‐art in downstream processing of monoclonal antibodies: Process trends in design and validation

PA Marichal‐Gallardo, MM Alvarez - Biotechnology progress, 2012 - Wiley Online Library
Monoclonal antibodies (mAbs) are the most important family of biopharmaceutical
compounds in terms of market share. At present, 30 mAbs have been approved and are now …

Critical Mineral Separations: Opportunities for Membrane Materials and Processes to Advance Sustainable Economies and Secure Supplies

L Lair, JA Ouimet, M Dougher… - Annual Review of …, 2024 - annualreviews.org
Sustainable energy solutions and electrification are driving increased demand for critical
minerals. Unfortunately, current mineral processing techniques are resource intensive, use …

Composite materials comprising supported porous gels

RF Childs, AM Mika, J Zhou, EN Komkova… - US Patent …, 2008 - Google Patents
(51) Int. Cl. EP O664732 B1 3/1997 CI2N II/02(2006.01) JP 62O14903 1, 1987 CI2N
II/08(2006.01) JP 62039636 2, 1987 C07K L/4(2006.01) JP O1070 108 3, 1989 C07K …

Recent developments in membrane-based separations in biotechnology processes

AS Rathore, A Shirke - Preparative Biochemistry and …, 2011 - Taylor & Francis
Membrane-based separations are the most ubiquitous unit operations in biotech processes.
There are several key reasons for this. First, they can be used with a large variety of …

Performance investigation of hydrophilic regenerated cellulose ultrafiltration membranes with excellent anti-fouling property via hydrolysis technology

S Zheng, S Yang, Z Ouyang, T Chen, Y Kuang… - Journal of …, 2023 - Elsevier
To obtain ultrafiltration (UF) membranes with excellent separation performances and
antifouling properties, regenerated cellulose (RC) membranes with intrinsic hydrophilicity …

Recent progress in the hydrophilic modification of alumina membranes for protein separation and purification

NF Ishak, NA Hashim, MHD Othman, P Monash… - Ceramics …, 2017 - Elsevier
In general, alumina membranes have been extensively developed for protein separation
and purification. Alumina membranes, which naturally feature a moderate hydrophilic …

Separation of lysozyme from chicken egg white using ultrafiltration

Y Wan, J Lu, Z Cui - Separation and Purification technology, 2006 - Elsevier
Using a methodology based on the combination of recently developed parameter scanning
ultrafiltration with carrier phase ultrafiltration (CPUF), this article examines the separation of …

Stable composite material comprising supported porous gels

AM Mika, MS Wang, RF Childs - US Patent 8,133,840, 2012 - Google Patents
This invention relates to a stable composite material compris ing a Support member that has
a plurality of pores extending through the Support member, and a macroporous crosslinked …

Protein separation using ultrafiltration—an example of multi-scale complex systems

Z Cui - China Particuology, 2005 - Elsevier
In this mini-review, the complexity of protein fractionation using ultrafiltration is discussed.
The coupling of the system hydrodynamics, boundary layer transport, membrane …

Desalination and recovery of iminodiacetic acid (IDA) from its sodium chloride mixtures by nanofiltration

J Luo, S Wei, Y Su, X Chen, Y Wan - Journal of membrane science, 2009 - Elsevier
The desalination of model solutions containing iminodiacetic acid (IDA) and NaCl was
examined using three commercial nanofiltration (NF) membranes (NF270, Desal-5 DL …