Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain

JA Letts, LA Sazanov - Nature structural & molecular biology, 2017 - nature.com
The oxidative phosphorylation electron transport chain (OXPHOS-ETC) of the inner
mitochondrial membrane is composed of five large protein complexes, named CI–CV. These …

Thermochemistry of proton-coupled electron transfer reagents and its implications

JJ Warren, TA Tronic, JM Mayer - Chemical reviews, 2010 - ACS Publications
Many, if not most, redox reactions are coupled to proton transfers. This includes most
common sources of chemical potential energy, from the bioenergetic processes that power …

[HTML][HTML] Energy conservation via electron bifurcating ferredoxin reduction and proton/Na+ translocating ferredoxin oxidation

W Buckel, RK Thauer - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2013 - Elsevier
The review describes four flavin-containing cytoplasmatic multienzyme complexes from
anaerobic bacteria and archaea that catalyze the reduction of the low potential ferredoxin by …

[HTML][HTML] Cytochrome b6f–Orchestrator of photosynthetic electron transfer

LA Malone, MS Proctor, A Hitchcock, CN Hunter… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Cytochrome b 6 f (cytb 6 f) lies at the heart of the light-dependent reactions of oxygenic
photosynthesis, where it serves as a link between photosystem II (PSII) and photosystem I …

How to make a living from anaerobic ammonium oxidation

B Kartal, NM de Almeida, WJ Maalcke… - FEMS microbiology …, 2013 - academic.oup.com
Anaerobic ammonium-oxidizing (anammox) bacteria primarily grow by the oxidation of
ammonium coupled to nitrite reduction, using CO2 as the sole carbon source. Although they …

Structure and mechanism of respiratory III–IV supercomplexes in bioenergetic membranes

P Brzezinski, A Moe, P Adelroth - Chemical reviews, 2021 - ACS Publications
In the final steps of energy conservation in aerobic organisms, free energy from electron
transfer through the respiratory chain is transduced into a proton electrochemical gradient …

Molecular mechanisms of superoxide production by the mitochondrial respiratory chain

S Dröse, U Brandt - … : nuclear-encoded genes, enzyme regulation, and …, 2012 - Springer
The mitochondrial respiratory chain is a major source of reactive oxygen species (ROS) in
eukaryotic cells. Mitochondrial ROS production associated with a dysfunction of respiratory …

Catalytic Reactions and Energy Conservation in the Cytochrome bc1 and b6f Complexes of Energy-Transducing Membranes

M Sarewicz, S Pintscher, R Pietras, A Borek… - Chemical …, 2021 - ACS Publications
This review focuses on key components of respiratory and photosynthetic energy-
transduction systems: the cytochrome bc 1 and b 6 f (Cyt bc 1/b 6 f) membranous …

Modelling mitochondrial ROS production by the respiratory chain

JP Mazat, A Devin, S Ransac - Cellular and Molecular Life Sciences, 2020 - Springer
ROS (superoxide and oxygen peroxide in this paper) play a dual role as signalling
molecules and strong oxidizing agents leading to oxidative stress. Their production mainly …

[HTML][HTML] Superoxide generation by complex III: from mechanistic rationales to functional consequences

L Bleier, S Dröse - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2013 - Elsevier
Apart from complex I (NADH: ubiquinone oxidoreductase) the mitochondrial cytochrome bc
1 complex (complex III; ubiquinol: cytochrome c oxidoreductase) has been identified as the …