Learning dynamical models of single and collective cell migration: a review

D Brückner, CP Broedersz - Reports on Progress in Physics, 2024 - iopscience.iop.org
Single and collective cell migration are fundamental processes critical for physiological
phenomena ranging from embryonic development and immune response to wound healing …

A comparison of computational models for eukaryotic cell shape and motility

WR Holmes, L Edelstein-Keshet - PLoS computational biology, 2012 - journals.plos.org
Eukaryotic cell motility involves complex interactions of signalling molecules, cytoskeleton,
cell membrane, and mechanics interacting in space and time. Collectively, these …

Multi-scale modelling of cancer cell intravasation: the role of cadherins in metastasis

I Ramis-Conde, MAJ Chaplain, ARA Anderson… - Physical …, 2009 - iopscience.iop.org
Transendothelial migration is a crucial process of the metastatic cascade in which a
malignant cell attaches itself to the endothelial layer forming the inner wall of a blood or …

A model of fibroblast motility on substrates with different rigidities

IV Dokukina, ME Gracheva - Biophysical journal, 2010 - cell.com
To function efficiently in the body, the biological cells must have the ability to sense the
external environment. Mechanosensitivity toward the extracellular matrix was identified as …

Computational approaches to substrate-based cell motility

F Ziebert, IS Aranson - npj Computational Materials, 2016 - nature.com
Substrate-based crawling motility of eukaryotic cells is essential for many biological
functions, both in develo** and mature organisms. Motility dysfunctions are involved in …

On the effect of substrate curvature on cell mechanics

JA Sanz-Herrera, P Moreo, JM García-Aznar… - Biomaterials, 2009 - Elsevier
Cell movement on a substrate or within the extracellular matrix is the phenomenological
response to a biochemical signals' cascade transcripted into biophysical processes and …

Modeling cell movement and chemotaxis using pseudopod-based feedback

MP Neilson, JA Mackenzie, SD Webb, RH Insall - SIAM Journal on Scientific …, 2011 - SIAM
A computational framework is presented for the simulation of eukaryotic cell migration and
chemotaxis. An empirical pattern formation model, based on a system of nonlinear reaction …

Signaling pathways that control cell migration: models and analysis

ES Welf, JM Haugh - Wiley Interdisciplinary Reviews: Systems …, 2011 - Wiley Online Library
Dissecting the intracellular signaling mechanisms that govern the movement of eukaryotic
cells presents a major challenge, not only because of the large number of molecular players …

Computational models of sprouting angiogenesis and cell migration: towards multiscale mechanochemical models of angiogenesis

TAM Heck, MM Vaeyens… - … Modelling of Natural …, 2015 - mmnp-journal.org
Angiogenesis, the formation of new bloods vessels from the existing vasculature, is a
process that is essential during development and regeneration of tissues, and that plays a …

Cell-biomaterial mechanical interaction in the framework of tissue engineering: insights, computational modeling and perspectives

JA Sanz-Herrera, E Reina-Romo - International journal of molecular …, 2011 - mdpi.com
Tissue engineering is an emerging field of research which combines the use of cell-seeded
biomaterials both in vitro and/or in vivo with the aim of promoting new tissue formation or …