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An updated review on diverse range of biological activities of 1, 2, 4-triazole derivatives: Insight into structure activity relationship
Abstract Since its discovery 1, 2, 4-triazole ring has emerged as a prominent heterocyclic
scaffold in medicinal chemistry. It possesses a wide spectrum of biological activities such as …
scaffold in medicinal chemistry. It possesses a wide spectrum of biological activities such as …
Exploring diverse frontiers: Advancements of bioactive 4-aminoquinoline-based molecular hybrids in targeted therapeutics and beyond
Amongst heterocyclic compounds, quinoline and its derivatives are advantaged scaffolds
that appear as a significant assembly motif for develo** new drug entities. Aminoquinoline …
that appear as a significant assembly motif for develo** new drug entities. Aminoquinoline …
1, 3, 5‐Triazine: A versatile pharmacophore with diverse biological activities
S Singh, MK Mandal, A Masih, A Saha… - Archiv der …, 2021 - Wiley Online Library
Triazine and its derivatives have been the epicenter of chemotherapeutic molecules due to
their effective biological activities, such as antibacterial, fungicidal, antimalarial, anticancer …
their effective biological activities, such as antibacterial, fungicidal, antimalarial, anticancer …
Antitumor activity of s-triazine derivatives: A systematic review
Q Dai, Q Sun, X Ouyang, J Liu, L **, A Liu, B He, T Fan… - Molecules, 2023 - mdpi.com
1, 3, 5-triazine derivatives, also called s-triazines, are a series of containing-nitrogen
heterocyclic compounds that play an important role in anticancer drug design and …
heterocyclic compounds that play an important role in anticancer drug design and …
Membrane-active substituted triazines as antibacterial agents against Staphylococcus aureus with potential for low drug resistance and broad activity
A library of new naphthalimide–triazine analogues was synthesized as broad-spectrum
antibacterial agents to overcome drug resistance. Bioactivity assay reveals that derivative …
antibacterial agents to overcome drug resistance. Bioactivity assay reveals that derivative …
Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)-s-triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling …
Here, we synthesized a newseries of mono-and bis (dimethylpyrazolyl)-s-triazine
derivatives. The synthetic methodology involved the reaction of different mono-and …
derivatives. The synthetic methodology involved the reaction of different mono-and …
Recent advances in the biological activity of s-triazine core compounds
D Maliszewski, D Drozdowska - Pharmaceuticals, 2022 - mdpi.com
An effective strategy for successful chemotherapy relies on creating compounds with high
selectivity against cancer cells compared to normal cells and relatively low cytotoxicity. One …
selectivity against cancer cells compared to normal cells and relatively low cytotoxicity. One …
Novel sulfonamide–triazine hybrid derivatives: docking, synthesis, and biological evaluation as anticancer agents
The biological benefits of trisubstituted 1, 3, 5-triazine derivatives include their ability to
reduce inflammation and fight cancer. A unique series of sulfonamide–triazine hybrid …
reduce inflammation and fight cancer. A unique series of sulfonamide–triazine hybrid …
Nitrogen‐Containing Heterocyclic Scaffolds as EGFR Inhibitors: Design Approaches, Molecular Docking, and Structure‐Activity Relationships
Cancer is a wide collection of diseases and among the numerous pathways involved in
cancer pathogenesis, pathway involving epidermal growth factor receptor (EGFR) is one of …
cancer pathogenesis, pathway involving epidermal growth factor receptor (EGFR) is one of …
Functionalized triazines and tetrazines: Synthesis and applications
J Mondal, A Sivaramakrishna - Topics in Current Chemistry, 2022 - Springer
The molecules possessing triazine and tetrazine moieties belong to a special class of
heterocyclic compounds. Both triazines and tetrazines are building blocks and have …
heterocyclic compounds. Both triazines and tetrazines are building blocks and have …