Precision medicine is a new frontier in healthcare that uses scientific methods to customize
medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person …

The global burden caused by cardiovascular disease is substantial, with heart disease
representing the most common cause of death around the world. There remains a need to …

The inner surfaces of the human heart are covered by a complex network of muscular
strands that is thought to be a remnant of embryonic development,. The function of these …

Since myocardial fibers drive the electric signal propagation throughout the myocardium,
accurately modeling their arrangement is essential for simulating heart electrophysiology …

Background—Accurate knowledge of the human atrial fibrous structure is paramount in
understanding the mechanisms of atrial electric function in health and disease. Thus far …

Rule‐based methods are often used for assigning fiber orientation to cardiac anatomical
models. However, existing methods have been developed using data mostly from the left …

Two crucial factors for accurate numerical simulations of cardiac electromechanics, which
are also essential to reproduce the synchronous activity of the heart, are:(i) accounting for …

Atlases encode valuable anatomical and functional information from a population. In this
work, a bi-ventricular cardiac atlas was built from a unique data set, which consists of high …

The aim of this study was to implement a quantitative in vivo cardiac diffusion tensor imaging
(DTI) technique that was robust, reproducible, and feasible to perform in patients with …

Background Modeling the whole cardiac function involves the solution of several complex
multi-physics and multi-scale models that are highly computationally demanding, which call …