Photomechanical organic crystals transform light into mechanical work via solid-state
photochemical reactions. While many examples of photomechanical systems have been …

Here, we present the new application of solid-state Vibrational Circular Dichroism (VCD)
spectroscopy to differentiate several dutasteride (DS) solvatomorphs–the model active …

Peramivir is an effective antiviral drug for treating influenza A and B with the trihydrate form
as the solid serving. However, a small amount of dihydrate still exists during the …

A multi-kinase inhibitor, pazopanib (PAZ) is cocrystallized with cyclooxygenase (COX)
inhibitor fenamic acids to investigate the dissolution rate and inhibition of cell migration in …

Dabrafenib (DBF), an anticancer drug, exhibits isostructural properties in its hydrate (DBF⊃
H 2 O) and perhydrate (DBF⊃ H 2 O 2) forms, as revealed by single-crystal X-ray diffraction …

The progress and growth of drug discovery and development (DDD) in the past five decades
are reviewed in terms of the changing trends over the years. The importance of the …

In this work, the solid-form landscape of probucol is investigated by crystallization from
solutions in various solvents (methanol, ethanol, acetonitrile, and dichloromethane), under …

Molnupiravir (MPV) is a widely used oral anti-COVID-19 drug. Owing to the rotatable bonds
and the large number of acceptors and donors of hydrogen bonds in the molecular structure …

Ellagic acid (EA), a biologically active polyphenol abundant in various natural plants, has
been widely applied in diverse pharmacological systems. This study investigates cocrystals …

Trimethylglycine (glycine betaine, GB) is an important organic osmolyte that accumulates in
various plant species in response to environmental stresses and has significant potential as …