Renal toxicity associated with tenofovir use
S Rodriguez-Nóvoa, E Alvarez, P Labarga… - Expert opinion on drug …, 2010 - Taylor & Francis
Importance of the field: Tenofovir (TFV) is a nucleotide analogue widely used for the
treatment of HIV infection. Despite its proven efficacy and safety, cases of kidney tubular …
treatment of HIV infection. Despite its proven efficacy and safety, cases of kidney tubular …
Current status of antiretroviral therapy
Z Temesgen, D Warnke, MJ Kasten - Expert opinion on …, 2006 - Taylor & Francis
At present, there are 22 FDA-approved antiretroviral agents, which are categorised into four
classes of drugs. Several others are in various stages of basic and clinical development. The …
classes of drugs. Several others are in various stages of basic and clinical development. The …
Differential impact of adherence on long-term treatment response among naive HIV-infected individuals
Objectives: To examine the long-term impact of adherence on virologic, immunologic, and
dual response stratified by type of HAART regimen in treatment-naive patients starting …
dual response stratified by type of HAART regimen in treatment-naive patients starting …
Discordant responses to potent antiretroviral treatment in previously naive HIV-1-infected adults initiating treatment in resource-constrained countries: the antiretroviral …
Objectives: To assess the frequency of and risk factors for discordant responses at 6 months
on highly active antiretroviral therapy (HAART) in previously treatment-naive HIV patients …
on highly active antiretroviral therapy (HAART) in previously treatment-naive HIV patients …
[HTML][HTML] Role of the pharmacist in caring for patients with HIV/AIDS: clinical practice guidelines
Over the past decade, there have been numerous advances in HIV therapy, with 6 drug
classes comprising 24 individual antiretroviral agents now available. For patients who are …
classes comprising 24 individual antiretroviral agents now available. For patients who are …
Exploring mitochondrial nephrotoxicity as a potential mechanism of kidney dysfunction among HIV-infected patients on highly active antiretroviral therapy
HCF Côté, AB Magil, M Harris, BJ Scarth… - Antiviral …, 2006 - journals.sagepub.com
Background Tenofovir (TDF) exposure has been associated with renal dysfunction.
Mitochondrial nephrotoxicity was investigated as an underlying mechanism. Given the …
Mitochondrial nephrotoxicity was investigated as an underlying mechanism. Given the …
CD4 decline is associated with increased risk of cardiovascular disease, cancer, and death in virally suppressed patients with HIV
M Helleberg, G Kronborg, CS Larsen… - Clinical infectious …, 2013 - academic.oup.com
Background. The clinical implications of a considerable CD4 decline despite antiretroviral
treatment and viral suppression are unknown. We aimed to test the hypothesis that a major …
treatment and viral suppression are unknown. We aimed to test the hypothesis that a major …
A simplification trial switching from nucleoside reverse transcriptase inhibitors to once-daily fixed-dose abacavir/lamivudine or tenofovir/emtricitabine in HIV-1-infected …
E Martínez, JA Arranz, D Podzamczer… - JAIDS Journal of …, 2009 - journals.lww.com
Background: Data comparing abacavir/lamivudine versus tenofovir/emtricitabine in
antiretroviral-naive patients are controversial. We compared 48-week efficacy and safety of …
antiretroviral-naive patients are controversial. We compared 48-week efficacy and safety of …
Patients' characteristics and clinical implications of suboptimal CD4 T-cell gains after 1 year of successful antiretroviral therapy
To describe characteristics and prognosis of patients with suboptimal immunological
response to combined antiretroviral therapy (CART). Using data from a multicenter cohort …
response to combined antiretroviral therapy (CART). Using data from a multicenter cohort …
A review of management of inflammation in the HIV population
J Slim, CF Saling - BioMed research international, 2016 - Wiley Online Library
Advancements in antiretroviral therapy have drastically increased the life expectancy for
those infected with HIV. Today, a new subgroup of older patients with long‐term controlled …
those infected with HIV. Today, a new subgroup of older patients with long‐term controlled …