Cardiac 123I-metaiodobenzylguanidine (MIBG) scintigraphy in Parkinson's disease: A comprehensive review

J Pitton Rissardo, AL Fornari Caprara - Brain Sciences, 2023 - mdpi.com
Cardiac sympathetic denervation, as documented on 123I-metaiodobenzylguanidine (MIBG)
myocardial scintigraphy, is relatively sensitive and specific for distinguishing Parkinson's …

The Park Sleep subtype in Parkinson's disease: from concept to clinic

P Tall, MA Qamar, I Rosenzweig, V Raeder… - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction The heterogeneity of Parkinson's disease (PD) is evident from
descriptions of non-motor (NMS) subtypes and Park Sleep, originally identified by Sauerbier …

Occipital hypometabolism is a risk factor for conversion to Parkinson's disease in isolated REM sleep behaviour disorder

G Carli, SK Meles, A Janzen, E Sittig, RV Kogan… - European Journal of …, 2023 - Springer
Purpose Isolated REM sleep behaviour disorder (iRBD) patients are at high risk of
develo** clinical syndromes of the α-synuclein spectrum. Progression markers are …

Reduced Gastric Contraction in Rapid‐Eye‐Movement Sleep Behavior Disorder and De Novo Parkinson's Disease

WH Oertel, E Paule, T Hasemann, E Sittig… - Movement …, 2024 - Wiley Online Library
Background Reduced gastric motility in Parkinson's disease (PD) has been reported, but
hardly any study exists in subjects with isolated rapid‐eye‐movement (REM) sleep behavior …

Imaging Biomarkers in Prodromal and Earliest Phases of Parkinson's Disease

H Theis, N Pavese, I Rektorová… - Journal of Parkinson's …, 2024 - content.iospress.com
Assessing imaging biomarker in the prodromal and early phases of Parkinson's disease
(PD) is of great importance to ensure an early and safe diagnosis. In the last decades …

Reduced cardiac 123I-MIBG uptake is a robust biomarker of Lewy body disease in isolated rapid eye movement sleep behaviour disorder

T Miyamoto, M Miyamoto - Brain Communications, 2024 - academic.oup.com
Cardiac 123I-MIBG scintigraphy is used to assess the function of postganglionic presynaptic
cardiac sympathetic nerve endings. 123I-MIBG cardiac uptake is markedly reduced in …

Definition and diagnosis of Parkinson's disease: guideline “Parkinson's disease” of the German Society of Neurology

F Hopfner, G Höglinger, C Trenkwalder - Journal of Neurology, 2024 - Springer
Background Accurate definition and operational criteria for diagnosing Parkinson's disease
(PD) are crucial for evidence-based, patient-centered care. Objective To offer evidence …

[PDF][PDF] Wolfgang H. Oertel, Annette Janzen1, Martin T. Henrich1, 3, 4, Fanni F. Geibl1, 3, 4, Elisabeth Sittig1, Sanne K. Meles5, Giulia Carli6, Klaus Leenders6

J Booij, DJ Surmeier, L Timmermann, M Strupp - Nature Communications, 2024 - d-nb.info
Isolated REM Sleep Behavior Disorder (iRBD) is considered a prodrome of Parkinson's
disease (PD). We investigate whether the potentially diseasemodifying compound acetyl-DL …

Research progress on neuromolecular imaging of REM sleep behavior disorder

C Geng, H Zhang - Frontiers in Neurology, 2022 - frontiersin.org
Idiopathic rapid eye movement sleep behavior disorder (iRBD) is an important non-motor
complication of Parkinson's disease. At the same time, iRBD is considered to be the …