Transplantation, the gold standard intervention for organ failure, is a clinical field that is ripe
for applications of gene therapy. One of the major challenges in applying gene therapy to …

In modern cardiovascular research, isolated perfused hearts have become cost-effective
and highly reproducible tools to investigate the mechanisms of cardiovascular diseases …

Heart transplantation remains a critical therapy for patients with end-stage heart failure,
offering incremental survival and improved quality of life. One of the key components behind …

The use of ex vivo machine perfusion for organ preservation has significantly improved solid
organ transplantation outcomes. This modality of organ preservation has increased the …

Preclinical disease models are important for the advancement of therapeutics towards
human clinical trials. One of the difficult tasks of develo** a well-characterized model is …