Sexual differentiation of the rodent brain: dogma and beyond
Steroid hormones of gonadal origin act on the neonatal brain to produce sex differences that
underlie adult reproductive physiology and behavior. Neuronal sex differences occur on a …
underlie adult reproductive physiology and behavior. Neuronal sex differences occur on a …
Foxp2 regulates gene networks implicated in neurite outgrowth in the develo** brain
Forkhead-box protein P2 is a transcription factor that has been associated with intriguing
aspects of cognitive function in humans, non-human mammals, and song-learning birds …
aspects of cognitive function in humans, non-human mammals, and song-learning birds …
[HTML][HTML] A novel basement membrane-related gene signature for prognosis of lung adenocarcinomas
Z Zhang, H Zhu, X Wang, S Lin, C Ruan… - Computers in biology and …, 2023 - Elsevier
Background Lung adenocarcinoma (LUAD) remains a global health concern with its poor
prognosis and high mortality. Whether tumor cells invade through the basement membrane …
prognosis and high mortality. Whether tumor cells invade through the basement membrane …
MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells
Vitamin D deficiency is associated with the high risk of colon cancer and a variety of other
diseases. The active vitamin D metabolite 1α, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3) …
diseases. The active vitamin D metabolite 1α, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3) …
NELL2 modulates cell proliferation and apoptosis via ERK pathway in the development of benign prostatic hyperplasia
J Liu, D Liu, X Zhang, Y Li, X Fu, W He, M Li… - Clinical …, 2021 - portlandpress.com
Benign prostatic hyperplasia (BPH) is a quite common illness but its etiology and
mechanism remain unclear. Neural epidermal growth factor-like like 2 (NELL2) plays …
mechanism remain unclear. Neural epidermal growth factor-like like 2 (NELL2) plays …
A novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma
Background Oncogenes promote the development of therapeutic targets against subsets of
cancers. Only several hundred oncogenes have been identified, primarily via mutation …
cancers. Only several hundred oncogenes have been identified, primarily via mutation …
Identification of key molecular targets that correlate with breast cancer through bioinformatic methods
W Tang, X Guo, L Niu, D Song, B Han… - The Journal of Gene …, 2020 - Wiley Online Library
Background The present study aimed to identify key molecular targets of breast cancer for
targeted treatment and to improve the survival rate. Methods Overlapped difference …
targeted treatment and to improve the survival rate. Methods Overlapped difference …
Cancer Stem Cell Phenotypes in ER+ Breast Cancer Models Are Promoted by PELP1/AIB1 Complexes
Proline, glutamic acid, leucine-rich protein 1 (PELP1) is overexpressed in approximately
80% of invasive breast tumors. PELP1 dynamically shuttles between the nucleus and …
80% of invasive breast tumors. PELP1 dynamically shuttles between the nucleus and …
[HTML][HTML] NELL2 function in axon development of hippocampal neurons
HR Kim, DH Kim, JY An, D Kang, JW Park… - Molecules and cells, 2020 - Elsevier
Neurons have multiple dendrites and single axon. This neuronal polarity is gradually
established during early processes of neuronal differentiation: generation of multiple …
established during early processes of neuronal differentiation: generation of multiple …
[HTML][HTML] Transcriptional regulatory role of NELL2 in preproenkephalin gene expression
CM Ha, DH Kim, TH Lee, HR Kim, J Choi, Y Kim… - Molecules and cells, 2022 - Elsevier
Preproenkephalin (PPE) is a precursor molecule for multiple endogenous opioid peptides
Leu-enkephalin (ENK) and Met-ENK, which are involved in a wide variety of modulatory …
Leu-enkephalin (ENK) and Met-ENK, which are involved in a wide variety of modulatory …