Sexual differentiation of the rodent brain: dogma and beyond

KM Lenz, BM Nugent, MM McCarthy - Frontiers in neuroscience, 2012 - frontiersin.org
Steroid hormones of gonadal origin act on the neonatal brain to produce sex differences that
underlie adult reproductive physiology and behavior. Neuronal sex differences occur on a …

Foxp2 regulates gene networks implicated in neurite outgrowth in the develo** brain

SC Vernes, PL Oliver, E Spiteri, HE Lockstone… - PLoS …, 2011 - journals.plos.org
Forkhead-box protein P2 is a transcription factor that has been associated with intriguing
aspects of cognitive function in humans, non-human mammals, and song-learning birds …

[HTML][HTML] A novel basement membrane-related gene signature for prognosis of lung adenocarcinomas

Z Zhang, H Zhu, X Wang, S Lin, C Ruan… - Computers in biology and …, 2023 - Elsevier
Background Lung adenocarcinoma (LUAD) remains a global health concern with its poor
prognosis and high mortality. Whether tumor cells invade through the basement membrane …

MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells

S Alvarez-Díaz, N Valle… - Human molecular …, 2012 - academic.oup.com
Vitamin D deficiency is associated with the high risk of colon cancer and a variety of other
diseases. The active vitamin D metabolite 1α, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3) …

NELL2 modulates cell proliferation and apoptosis via ERK pathway in the development of benign prostatic hyperplasia

J Liu, D Liu, X Zhang, Y Li, X Fu, W He, M Li… - Clinical …, 2021 - portlandpress.com
Benign prostatic hyperplasia (BPH) is a quite common illness but its etiology and
mechanism remain unclear. Neural epidermal growth factor-like like 2 (NELL2) plays …

A novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma

DG Piqué, C Montagna, JM Greally, JC Mar - British journal of cancer, 2019 - nature.com
Background Oncogenes promote the development of therapeutic targets against subsets of
cancers. Only several hundred oncogenes have been identified, primarily via mutation …

Identification of key molecular targets that correlate with breast cancer through bioinformatic methods

W Tang, X Guo, L Niu, D Song, B Han… - The Journal of Gene …, 2020 - Wiley Online Library
Background The present study aimed to identify key molecular targets of breast cancer for
targeted treatment and to improve the survival rate. Methods Overlapped difference …

Cancer Stem Cell Phenotypes in ER+ Breast Cancer Models Are Promoted by PELP1/AIB1 Complexes

TH Truong, H Hu, NA Temiz, KM Hagen… - Molecular Cancer …, 2018 - aacrjournals.org
Proline, glutamic acid, leucine-rich protein 1 (PELP1) is overexpressed in approximately
80% of invasive breast tumors. PELP1 dynamically shuttles between the nucleus and …

[HTML][HTML] NELL2 function in axon development of hippocampal neurons

HR Kim, DH Kim, JY An, D Kang, JW Park… - Molecules and cells, 2020 - Elsevier
Neurons have multiple dendrites and single axon. This neuronal polarity is gradually
established during early processes of neuronal differentiation: generation of multiple …

[HTML][HTML] Transcriptional regulatory role of NELL2 in preproenkephalin gene expression

CM Ha, DH Kim, TH Lee, HR Kim, J Choi, Y Kim… - Molecules and cells, 2022 - Elsevier
Preproenkephalin (PPE) is a precursor molecule for multiple endogenous opioid peptides
Leu-enkephalin (ENK) and Met-ENK, which are involved in a wide variety of modulatory …