Pneumococcal polysaccharide vaccines (PPVs) and conjugate vaccines (PCVs), of which
PPV23 and PCV13 are the current front runners, have had a significant, beneficial impact on …

Extracellular vesicles are produced by many pathogenic microorganisms and have varied
functions that include secretion and release of microbial factors, which contribute to …

The increasing incidence of infections caused by antibiotic-resistant bacteria from multiple
species, together with the paucity of new antibiotics in the development pipeline, indicates …

Current vaccination against Streptococcus pneumoniae uses vaccines based on capsular
polysaccharides from selected serotypes and has led to nonvaccine serotype replacement …

Infections by opportunistic bacteria have significant contributions to morbidity and mortality
of hospitalized patients and also lead to high expenses in healthcare. In this setting, one of …

Visceral Leishmaniasis (VL) is a neglected tropical disease of public health importance in
the Indian subcontinent. Despite consistent elimination initiatives, the disease has not yet …

ABSTRACT CD4+ T-cell mechanisms are implied in protection against pneumococcal
colonization; however, their target antigens and function are not well defined. In contrast to …

Glycoconjugate vaccines are made of carbohydrate antigens covalently bound to a carrier
protein to enhance their immunogenicity. Among the different carrier proteins tested in …

The emergence of antibiotic-resistant pathogenic bacteria is a healthcare problem
worldwide. We evaluated the antimicrobial activity of rhodomyrtone, an acylphloroglucinol …

Fate of biofilm sloughing was assessed in a laboratory-scale (LS) integrated fixed-film
sequencing batch reactor (IF-SBR) treating synthetic wastewater and in a full-scale (FS) …