Precision diagnostics: moving towards protein biomarker signatures of clinical utility in cancer

CAK Borrebaeck - Nature Reviews Cancer, 2017 - nature.com
Interest in precision diagnostics has been fuelled by the concept that early detection of
cancer would benefit patients; that is, if detected early, more tumours should be resectable …

[HTML][HTML] Biomarkers in the diagnosis of pancreatic cancer: Are we closer to finding the golden ticket?

RS O'Neill, A Stoita - World journal of gastroenterology, 2021 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is a leading cause of cancer related mortality on a global scale. The
disease itself is associated with a dismal prognosis, partly due to its silent nature resulting in …

Early diagnosis of pancreatic cancer: challenges and new developments

S Kaur, MJ Baine, M Jain, AR Sasson… - Biomarkers in …, 2012 - Taylor & Francis
Pancreatic cancer is a lethal malignancy with its incidence almost equivalent to mortality.
The complex pathophysiology, absence of early diagnostic and prognostic markers and …

[HTML][HTML] Screening and early diagnosis of osteoporosis through X-ray and ultrasound based techniques

P Pisani, MD Renna, F Conversano… - World journal of …, 2013 - ncbi.nlm.nih.gov
Effective prevention and management of osteoporosis would require suitable methods for
population screenings and early diagnosis. Current clinically-available diagnostic methods …

Serum biomarker signature-based liquid biopsy for diagnosis of early-stage pancreatic cancer

LD Mellby, AP Nyberg, JS Johansen… - Journal of Clinical …, 2018 - ascopubs.org
Purpose Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, with a 5-year
survival of< 10% because of diffuse symptoms leading to late-stage diagnosis. That survival …

[HTML][HTML] Blood biomarkers for differential diagnosis and early detection of pancreatic cancer

FN Al-Shaheri, MSS Alhamdani, AS Bauer… - Cancer treatment …, 2021 - Elsevier
Pancreatic cancer is currently the most lethal tumor entity and case numbers are rising. It will
soon be the second most frequent cause of cancer-related death in the Western world …

[HTML][HTML] Update on the management of pancreatic cancer: surgery is not enough

D Ansari, A Gustafsson, R Andersson - World journal of …, 2015 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of death in cancer
and has a 5-year survival of< 5%. Only about 15% of the patients present with a resectable …

Sequential validation of blood-based protein biomarker candidates for early-stage pancreatic cancer

M Capello, LE Bantis, G Scelo, Y Zhao… - JNCI: Journal of the …, 2017 - academic.oup.com
Background: CA19-9, which is currently in clinical use as a pancreatic ductal
adenocarcinoma (PDAC) biomarker, has limited performance in detecting early-stage …

A novel serum metabolomics-based diagnostic approach to pancreatic cancer

T Kobayashi, S Nishiumi, A Ikeda, T Yoshie… - … , biomarkers & prevention, 2013 - AACR
Background: To improve the prognosis of patients with pancreatic cancer, more accurate
serum diagnostic methods are required. We used serum metabolomics as a diagnostic …

Current applications of antibody microarrays

Z Chen, T Dodig-Crnković, JM Schwenk, S Tao - Clinical proteomics, 2018 - Springer
The concept of antibody microarrays is one of the most versatile approaches within
multiplexed immunoassay technologies. These types of arrays have increasingly become an …