Introduction T HE pituitary gonadotropins, LH and FSH, play a central role in the mammalian
reproductive process. Synthesized in the gonadotropes of the pituitary, the gonadotropins …

Human chorionic gonadotropin (hCG) is the first hormonal message from the placenta to the
mother. It is detectable in maternal blood two days after implantation and behaves like an …

Luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating
hormone (TSH) from pituitary and chorionic gonadotropin (CG) from placenta are a family of …

Normal pregnancy is characterized by an early expansion of regulatory T cells (Tregs),
which is known to contribute to fetal tolerance. However, mechanisms and factors behind …

To study the structure-function relationships of follitropin (FSH), we expressed the hormone
in a heterologous cell system. A genomic clone bearing a 3.7-kilobase FSHβ insert …

We have elucidated the structures of the anionic asparagine-linked oligosaccharides
present on the glycoprotein hormones lutropin (luteinizing hormone), follitropin (follicle …

I. Introduction C HORIONIC gonadotropin (CG) is a placental hormone that maintains the
corpus luteum of pregnancy. Because CG is expressed at high levels soon after fertilization …

Leukemia inhibitory factor (LIF) is a multifunctional glycoprotein strongly associated with
normal implantation in the mouse. We have recently determined that LIF is expressed in the …

Human chorionic gonadotropin (hCG) is a member of a family of heterodimeric glycoprotein
hormones that have a common alpha subunit but differ in their hormone-specific beta …

The chorionic gonadotropin beta (CG beta) subunit is encoded by a multigene cluster
composed of six homologous sequences (genes or pseudogenes). They are primarily …