Role of aptamer technology in extracellular vesicle biology and therapeutic applications
Extracellular vesicles (EVs) are cell-derived nanosized membrane-bound vesicles that are
important intercellular signalling regulators in local cell-to-cell and distant cell-to-tissue …
important intercellular signalling regulators in local cell-to-cell and distant cell-to-tissue …
DNA‐Based Nanocarriers to Sequester Altered microRNAs in Cardiac Dysfunction
A Postigo, N Hernández‐Bellido… - Advanced …, 2024 - Wiley Online Library
MicroRNAs (miRs) play a critical role in modulating gene expression across biological
processes, including cardiac aging and disease. As such, miRs have demonstrated …
processes, including cardiac aging and disease. As such, miRs have demonstrated …
Intracellular delivery of a phospholamban-targeting aptamer using cardiomyocyte-internalizing aptamers
T Honda, H Sakai, M Inui - European Journal of Pharmacology, 2024 - Elsevier
The sarco (endo) plasmic reticulum Ca 2+-ATPase 2a (SERCA2a)–phospholamban (PLN)
system within the sarcoplasmic reticulum is crucial for regulating intracellular Ca 2+ cycling …
system within the sarcoplasmic reticulum is crucial for regulating intracellular Ca 2+ cycling …
Identification of In Vivo Internalizing Cardiac-Specific RNA Aptamers
C Narayan, LH Lin, MN Barros, TC Gilbert… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background: The pursuit of selective therapeutic delivery to target tissue types represents a
key goal in the treatment of a range of adverse health issues, including diseases afflicting …
key goal in the treatment of a range of adverse health issues, including diseases afflicting …