Qualitative Structure-Activity Relationships and 2D-QSAR Modeling of TNF-α Inhibition by Thalidomide Derivatives

K Dermeche, N Tchouar, S Belaidi… - Journal of …, 2015 - ingentaconnect.com
Thalidomide is a tumor necrosis factor alpha (TNF-α) inhibitor which has been found to have
abilities against tumor growth, inflammation. QSAR studies have been performed on twenty …

In silico investigation by conceptual DFT and molecular docking of antitrypanosomal compounds for understanding cruzain inhibition

T Salah, S Belaidi, N Melkemi, I Daoud… - Journal of Theoretical …, 2016 - World Scientific
Current knowledge about Chagas disease, the potentially life-threatening illness caused by
the protozoan parasite (Trypanosoma cruzi), has led to the development of new drugs and …

Structure activity/property relationships of pyrazole derivatives by MPO and QSAR methods for drug design

R Hanachi, S Boughdiri, S Belaidi… - Research Journal of …, 2015 - elibrary.ru
Molecular geometry, electronic structure, effect of the substitution and structure/Property/
activity relationships for pyrazole derivatives, have been studied by molecular mechanics …

Conformational analysis and qsar modeling of 14-membered macrolide analogues against mycobacterium tuberculosis

K Zitouni, S Belaidi, A Kerassa - Journal of Fundamental and Applied …, 2020 - ajol.info
Electronic structures, effect of the substitution and structure physical-chemistry properties
relationship for macrolide derivatives, have been studied by PM3 and ab initio methods. In …

Structural exploration and study of the QSAR properties of several series of macrolide antibiotics.

K Zitouni - 2021 - thesis.univ-biskra.dz
In this work a fundamental and original research on the 14-membered macrolide, the aim is
to predict the reactivity and biological activity of the compound studied and its derivatives …

[PDF][PDF] Research Journal of Pharmaceutical, Biological and Chemical Sciences

V Jagathi, GD Rao, PS Praveen, CHM Babu - researchgate.net
Molecular geometry, electronic structure, effect of the substitution and structure/Property/
activity relationships for pyrazole derivatives, have been studied by molecular mechanics …

[PDF][PDF] Research Journal of Pharmaceutical, Biological and Chemical Sciences

D Gabric, M Sušić, D Katanec, IF Zore, VV Boras… - Risk, 2020 - researchgate.net
ABSTRACT large mid line incisional hernia is a challenging surgical issue, skin flap
necrosis, corsage feeling and chronic postoperative pain together with hernia recurrence …

[SITAATTI][C] DRUG LIKENESS SCORING AND STRUCTURE ACTIVITY/PROPERTY RELATIONSHIPS OF 1, 2, 3-TRIAZOLE DERIVATEVES AS AROMATASE …