Mechanisms governing autophagosome biogenesis
H Nakatogawa - Nature reviews Molecular cell biology, 2020 - nature.com
Autophagosomes are double-membrane vesicles newly formed during autophagy to engulf
a wide range of intracellular material and transport this autophagic cargo to lysosomes (or …
a wide range of intracellular material and transport this autophagic cargo to lysosomes (or …
Mechanism and medical implications of mammalian autophagy
Autophagy is a highly conserved catabolic process induced under various conditions of
cellular stress, which prevents cell damage and promotes survival in the event of energy or …
cellular stress, which prevents cell damage and promotes survival in the event of energy or …
The mammalian ULK1 complex and autophagy initiation
Autophagy is a vital lysosomal degradation pathway that serves as a quality control
mechanism. It rids the cell of damaged, toxic or excess cellular components, which if left to …
mechanism. It rids the cell of damaged, toxic or excess cellular components, which if left to …
Regulation of autophagy by mTOR signaling pathway
Autophagy plays a crucial role in maintaining cellular homeostasis, and is closely related to
the occurrence of variety of human diseases. It is known that autophagy occurs in response …
the occurrence of variety of human diseases. It is known that autophagy occurs in response …
Autophagy: The spotlight for cellular stress responses
Autophagy is an essential cellular mechanism which plays “housekee**” role in normal
physiological processes including removing of long lived, aggregated and misfolded …
physiological processes including removing of long lived, aggregated and misfolded …
Roles of autophagy in oxidative stress
HR Yun, YH Jo, J Kim, Y Shin, SS Kim… - International journal of …, 2020 - mdpi.com
Autophagy is a catabolic process for unnecessary or dysfunctional cytoplasmic contents by
lysosomal degradation pathways. Autophagy is implicated in various biological processes …
lysosomal degradation pathways. Autophagy is implicated in various biological processes …
Cell death signaling
In multicellular organisms, cell death is a critical and active process that maintains tissue
homeostasis and eliminates potentially harmful cells. There are three major types of …
homeostasis and eliminates potentially harmful cells. There are three major types of …
Autophagosome biogenesis: From membrane growth to closure
Autophagosome biogenesis involves de novo formation of a membrane that elongates to
sequester cytoplasmic cargo and closes to form a double-membrane vesicle (an …
sequester cytoplasmic cargo and closes to form a double-membrane vesicle (an …
Autophagy: an essential degradation program for cellular homeostasis and life
Y Chun, J Kim - Cells, 2018 - mdpi.com
Autophagy is a lysosome-dependent cellular degradation program that responds to a variety
of environmental and cellular stresses. It is an evolutionarily well-conserved and essential …
of environmental and cellular stresses. It is an evolutionarily well-conserved and essential …
Mechanisms of autophagy initiation
Autophagy is the process of cellular self-eating by a double-membrane organelle, the
autophagosome. A range of signaling processes converge on two protein complexes to …
autophagosome. A range of signaling processes converge on two protein complexes to …