Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey

R Kones - Drug design, development and therapy, 2011 - Taylor & Francis
A recent explosion in the amount of cardiovascular risk and incipient, undetected subclinical
cardiovascular pathology has swept across the globe. Nearly 70% of adult Americans are …

Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression …

M Briel, I Ferreira-Gonzalez, JJ You, PJ Karanicolas… - Bmj, 2009 - bmj.com
Objective To investigate the association between treatment induced change in high density
lipoprotein cholesterol and total death, coronary heart disease death, and coronary heart …

Efficacy of fibrates for cardiovascular risk reduction in persons with atherogenic dyslipidemia: a meta-analysis

M Lee, JL Saver, A Towfighi, J Chow, B Ovbiagele - Atherosclerosis, 2011 - Elsevier
BACKGROUND: Recent data suggest that non-targeted treatment with fibrates modestly
reduces the risk of incident cardiovascular events. However the effect of fibrate treatment …

Levels and changes of HDL cholesterol and apolipoprotein AI in relation to risk of cardiovascular events among statin-treated patients: a meta-analysis

SM Boekholdt, BJ Arsenault, GK Hovingh, S Mora… - Circulation, 2013 - Am Heart Assoc
Background—It is unclear whether levels of high-density lipoprotein cholesterol (HDL-C) or
apolipoprotein AI (apoA-I) remain inversely associated with cardiovascular risk among …

Cardiometabolic risk factors in young adults who were born preterm

M Sipola-Leppänen, M Vääräsmäki… - American journal of …, 2015 - academic.oup.com
Adults who were born preterm with a very low birth weight have higher blood pressure and
impaired glucose regulation later in life compared with those born at term. We investigated …

HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial

PM Ridker, J Genest, SM Boekholdt, P Libby, AM Gotto… - The Lancet, 2010 - thelancet.com
Background HDL-cholesterol concentrations are inversely associated with occurrence of
cardiovascular events. We addressed, using the JUPITER trial cohort, whether this …

HDL cholesterol subclasses, myocardial infarction, and mortality in secondary prevention: the Lipoprotein Investigators Collaborative

SS Martin, AA Khokhar, HT May… - European heart …, 2015 - academic.oup.com
Aims High-density lipoprotein (HDL) is highly heterogeneous and the link of its subclasses
to prognosis remains controversial. We aimed to rigorously examine the associations of HDL …

Association of serum triglyceride-to-HDL cholesterol ratio with carotid artery intima-media thickness, insulin resistance and nonalcoholic fatty liver disease in children …

L Pacifico, E Bonci, G Andreoli, S Romaggioli… - Nutrition, Metabolism …, 2014 - Elsevier
Background and aims The triglyceride (TG)/high-density lipoprotein-cholesterol (HDL-C)
ratio has been reported as a useful marker of atherogenic lipid abnormalities, insulin …

Beyond high-density lipoprotein cholesterol levels: evaluating high-density lipoprotein function as influenced by novel therapeutic approaches

EM DeGoma, RL degoma, DJ Rader - Journal of the American College of …, 2008 - jacc.org
A number of therapeutic strategies targeting high-density lipoprotein (HDL) cholesterol and
reverse cholesterol transport are being developed to halt the progression of atherosclerosis …

[HTML][HTML] Low levels of high-density lipoprotein cholesterol increase the risk of incident kidney disease and its progression

B Bowe, Y **e, H **an, S Balasubramanian, Z Al-Aly - Kidney international, 2016 - Elsevier
Available experimental evidence suggests a role for high-density lipoprotein cholesterol
(HDL-C) in incident chronic kidney disease (CKD) and its progression. However, clinical …