Free radical properties, source and targets, antioxidant consumption and health

G Martemucci, C Costagliola, M Mariano, L D'andrea… - Oxygen, 2022 - mdpi.com
Free radicals have acquired growing importance in the fields of biology and medicine. They
are produced during many different endogenous and exogenous processes. Mitochondria …

Oxidative stress, aging, antioxidant supplementation and their impact on human health: An overview

G Martemucci, P Portincasa, A Di Ciaula… - Mechanisms of Ageing …, 2022 - Elsevier
Aging is characterized by a progressive loss of tissue and organ function due to genetic and
environmental factors, nutrition, and lifestyle. Oxidative stress is one the most important …

[HTML][HTML] Anti-oxidant potential of plants and probiotic spp. in alleviating oxidative stress induced by H2O2

H Kumar, R Dhalaria, S Guleria, R Cimler… - Biomedicine & …, 2023 - Elsevier
Cells produce reactive oxygen species (ROS) as a metabolic by-product. ROS molecules
trigger oxidative stress as a feedback response that significantly initiates biological …

Does vitamin C influence neurodegenerative diseases and psychiatric disorders?

J Kocot, D Luchowska-Kocot, M Kiełczykowska, I Musik… - Nutrients, 2017 - mdpi.com
Vitamin C (Vit C) is considered to be a vital antioxidant molecule in the brain. Intracellular Vit
C helps maintain integrity and function of several processes in the central nervous system …

Mitochondrial cristae morphology reflecting metabolism, superoxide formation, redox homeostasis, and pathology

P Ježek, M Jabůrek, B Holendová… - Antioxidants & Redox …, 2023 - liebertpub.com
Significance: Mitochondrial (mt) reticulum network in the cell possesses amazing
ultramorphology of parallel lamellar cristae, formed by the invaginated inner mitochondrial …

Loss of mitochondrial function impairs lysosomes

J Demers-Lamarche, G Guillebaud, M Tlili… - Journal of biological …, 2016 - jbc.org
Alterations in mitochondrial function, as observed in neurodegenerative diseases, lead to
disrupted energy metabolism and production of damaging reactive oxygen species. Here …

[HTML][HTML] Iron load toxicity in medicine: from molecular and cellular aspects to clinical implications

GJ Kontoghiorghes - International journal of molecular sciences, 2023 - mdpi.com
Iron is essential for all organisms and cells. Diseases of iron imbalance affect billions of
patients, including those with iron overload and other forms of iron toxicity. Excess iron load …

Mitochondrial disease and endocrine dysfunction

J Chow, J Rahman, JC Achermann… - Nature Reviews …, 2017 - nature.com
Mitochondria are critical organelles for endocrine health; steroid hormone biosynthesis
occurs in these organelles and they provide energy in the form of ATP for hormone …

Iron deficiency beyond erythropoiesis: should we be concerned?

KM Musallam, AT Taher - Current medical research and opinion, 2018 - Taylor & Francis
Objective: To consider the key implications of iron deficiency for biochemical and
physiological functions beyond erythropoiesis. Methods: PubMed was searched for relevant …

Anthocyanins: From plant pigments to health benefits at mitochondrial level

V Bendokas, K Skemiene, S Trumbeckaite… - Critical Reviews in …, 2020 - Taylor & Francis
Anthocyanins are water-soluble pigments providing certain color for various plant parts,
especially in edible berries. Earlier these compounds were only known as natural food …