Chemotherapy side-effects: not all DNA damage is equal

WMC van den Boogaard, DSJ Komninos, WP Vermeij - Cancers, 2022 - mdpi.com
Simple Summary The number of children and adults with cancer that are completely cured is
still increasing thanks to effective anti-cancer therapy, but they may be confronted with the …

Chemotherapy: how to reduce its adverse effects while maintaining the potency?

Brianna, SH Lee - Medical Oncology, 2023 - Springer
Chemotherapy is one of the widely used anticancer treatments that involves the use of
powerful cytotoxic drugs to stop tumor growth by targeting rapidly dividing cells through …

Cardiotoxicity of anticancer drugs: molecular mechanisms and strategies for cardioprotection

MB Morelli, C Bongiovanni, S Da Pra… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy and targeted therapies have significantly improved the prognosis of
oncology patients. However, these antineoplastic treatments may also induce adverse …

Mitochondrial dysfunction at the crossroad of cardiovascular diseases and cancer

C Rocca, T Soda, EM De Francesco, M Fiorillo… - Journal of translational …, 2023 - Springer
A large body of evidence indicates the existence of a complex pathophysiological
relationship between cardiovascular diseases and cancer. Mitochondria are crucial …

Chemotherapy induced cardiotoxicity: a state of the art review on general mechanisms, prevention, treatment and recent advances in novel therapeutics

T Abdul-Rahman, A Dunham, H Huang… - Current Problems in …, 2023 - Elsevier
As medicine advances to employ sophisticated anticancer agents to treat a vast array of
oncological conditions, it is worth considering side effects associated with several …

Pesticides and cardiotoxicity. Where do we stand?

N Georgiadis, K Tsarouhas, C Tsitsimpikou… - Toxicology and applied …, 2018 - Elsevier
Cardiovascular diseases are among the most significant causes of mortality in humans.
Pesticides toxicity and risk for human health are controlled at a European level through a …

Adjuvant role of Salvia miltiorrhiza bunge in cancer chemotherapy: A review of its bioactive components, health-promotion effect and mechanisms

J Huang, J Zhang, C Sun, R Yang, M Sheng… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Chemotherapy is a common cancer treatment strategy.
However, its effectiveness is constrained by toxicity and adverse effects. The Lamiaceae …

A comprehensive overview on chemotherapy-induced cardiotoxicity: insights into the underlying inflammatory and oxidative mechanisms

A Nagy, D Börzsei, A Hoffmann, S Török… - … Drugs and Therapy, 2024 - Springer
While oncotherapy has made rapid progress in recent years, side effects of anti-cancer
drugs and treatments have also come to the fore. These side effects include cardiotoxicity …

[HTML][HTML] Cardio-oncology: mechanisms, drug combinations, and reverse cardio-oncology

Z Liang, Y He, X Hu - International journal of molecular sciences, 2022 - mdpi.com
Chemotherapy, radiotherapy, targeted therapy, and immunotherapy have brought hope to
cancer patients. With the prolongation of survival of cancer patients and increased clinical …

Late morbidity and mortality among medulloblastoma survivors diagnosed across three decades: a report from the childhood cancer survivor study

R Salloum, Y Chen, Y Yasui, R Packer… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE Treatment of medulloblastoma has evolved from surgery and radiotherapy to
contemporary multimodal regimens. However, the impact on long-term health outcomes …