Background Smoking is a well-established risk factor for chronic non-communicable
diseases. However, the relationship between cigarette smoking and the risk of develo** …

Aims Recent studies have suggested increased rates of depression in healthcare workers
(HCWs), with direct impact on care quality and productivity. The objective was to determine …

We examined the prospective associations between nicotine dependence and the likelihood
of psychiatric and substance use disorders in the general adult population. Participants …

Objectives Indoor air pollution exposure is harmful to people's physical and mental health,
especially in the elderly population. Depressive symptoms are the most common mental …

Background Major depressive disorder (MDD) is a highly prevalent psychiatric condition
characterised by a heterogeneous clinical presentation and an estimated twin-based …

The risk of depression could be evaluated through its multifactorial nature using the
polygenic score (PGS) approach. Assuming a “clinical continuum” hypothesis of mental …

Background This study explored the phenotypic association of mood disorders, including
major depressive disorder (MDD) and bipolar disorder (BPD), with a range of substance …

Background and aims Whether alcohol‐related DNA methylation has a causal effect on
psychiatric disorders has not been investigated. Furthermore, a comprehensive investigation …

Background Previous studies have shown that lifestyle was associated with depression.
Thus, the aim of this study was to examine the causality between multiple lifestyles and …

Objective The objective of this study was to estimate the prevalence of past alcohol use and
to evaluate patterns of alcohol use among Chinese adolescents. Methods 1,707 students …