This chapter deals with the synthesis of nucleosides (eg, the formation of N‐glycosides of
sugars such as d‐ribose or 2‐deoxy‐D‐ribose with heterocyclic nitrogen bases). The …

Typical nucleosides are initially obtained from the nucleic acids, DNA and RNA, by
enzymatic hydrolysis, and they are of great biological importance in metabolic pathways. 1 …

Four new benzamides, pyramidamycins AD (2–5) along with the new natural 3-
hydroxyquinoline-2-carboxamide (6) were isolated from the crude extract of Streptomyces …

Thymidine, deoxycytidine, deoxyadenosine, and deoxyguanosine have been prepared with
deuterium substitution at position 1'and at positions 1', 2', and 2" from deuteriated …

The photochemical [2+ 2] cycloaddition of chiral 3-chloro and 3-fluoro-5-hydroxymethyl-2 (5
H)-furanone to ethylene and acetylene has been studied. The effect of the halogen atom on …

Two routes have been devised for the first synthesis of 2', 2'-dideuterio-2'-deoxynucleosides.
First route involves the oxidation of an appropriately 3', 5'-protected ribonucleosides with …

Nucleosides isotopicallysubstituted at specific posi-tions are useful for mechanistic and
spectroscopic studies. In particular, isotopic substitution of thehydrogens at the C2'position …

Raney nickel-2H2O exchange reaction on an epimeric mixture of methyl α/β-D-
ribofuranoside [α/β=∼ 3: 10] 1 produced methyl 1#, 2, 3, 4#, 5, 5′-2H6-α/β-ribofuranoside 2 …

The conformational diversity of the sugar moieties in DNA is considered to be important in
the elucidation of sequence-specific DNA-protein or-drug recognition processes. Although …

A complete synthetic protocol as well as 1H-and 13C-NMR data on the monomer building
blocks used for the solid-phase synthesis of specifically 13C-labelled (99 atom% 13C) stem …